Pre_GI: BLASTP Hits

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Query: NC_008258:1076922:1093140 Shigella flexneri 5 str. 8401, complete genome

Start: 1093140, End: 1093877, Length: 738

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004337:1065609:107376010737601074497738Shigella flexneri 2a str. 301, complete genomehypothetical protein3e-122437
AC_000091:1083798:109912010991201099857738Escherichia coli W3110 DNA, complete genomepredicted zinc-binding hydrolase1e-121435
NC_000913:1087062:109810210981021098839738Escherichia coli K12, complete genomehypothetical protein1e-121435
NC_010468:2809125:281029628102962811033738Escherichia coli ATCC 8739, complete genomePHP domain protein6e-121433
NC_003198:1117687:113636411363641137101738Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein3e-111401
NC_010102:1979742:198177519817751982512738Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein3e-111401
NC_006511:1770000:177205117720511772788738Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCChypothetical protein3e-111401
NC_011080:1209935:122787512278751228612738Salmonella enterica subsp. enterica serovar Newport str. SL254,putative hydrolase3e-111401
NC_004631:1842050:184408218440821844819738Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein3e-111401
NC_006905:1186895:120617412061741206911738Salmonella enterica subsp. enterica serovar Choleraesuis strhypothetical protein3e-111401
NC_011149:1987291:198729119872911988028738Salmonella enterica subsp. enterica serovar Agona str. SL483,putative hydrolase3e-111401
NC_003197:1207597:122608812260881226825738Salmonella typhimurium LT2, complete genomehypothetical protein3e-111401
NC_011147:1763681:176723417672341767971738Salmonella enterica subsp. enterica serovar Paratyphi A strhydrolase3e-111401
NC_011205:2137696:214017221401722140909738Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853hydrolase3e-111401
NC_011294:2009388:201186420118642012601738Salmonella enterica subsp. enterica serovar Enteritidis strhydrolase3e-111401
NC_017046:1164176:118230111823011183038738Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein3e-111401
NC_016863:1165232:118354111835411184278738Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative hydrolase3e-111401
NC_016860:1205282:122377412237741224511738Salmonella enterica subsp. enterica serovar Typhimurium strputative hydrolase3e-111401
NC_016857:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative hydrolase3e-111401
NC_016856:1165941:118425011842501184987738Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative hydrolase3e-111401
NC_016832:1838220:184111718411171841854738Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hydrolase3e-111401
NC_016810:1163919:118222811822281182965738Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein3e-111401
NC_012125:2646792:264882426488242649561738Salmonella enterica subsp. enterica serovar Paratyphi C strainhydrolase3e-111401
NC_011094:1166271:118439511843951185132738Salmonella enterica subsp. enterica serovar Schwarzengrund strhydrolase3e-111400
NC_010067:1782998:178501217850121785749738Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein3e-110397
NC_011083:1216500:123043712304371231174738Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,putative hydrolase3e-110397
NC_013716:1178383:119628011962801197017738Citrobacter rodentium ICC168, complete genomeputative phosphoesterase5e-108390
NC_015968:1709680:171420017142001714937738Enterobacter asburiae LF7a chromosome, complete genomehydrolase ycdX3e-105381
NC_016514:1701273:170400717040071704744738Enterobacter cloacae EcWSU1 chromosome, complete genomeprotein YcdX2e-104378
NC_014121:2629075:264547226454722646209738Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completePHP family protein4e-104377
NC_015663:3466471:350030035003003501040741Enterobacter aerogenes KCTC 2190 chromosome, complete genomeputative hydrolase9e-104376
NC_010159:2546590:256620325662032566940738Yersinia pestis Angola, complete genomeputative phosphoesterase2e-96352
NC_004088:2491303:251107125110712511919849Yersinia pestis KIM, complete genomehypothetical protein1e-96352
NC_010465:2383219:240294024029402403677738Yersinia pseudotuberculosis YPIII, complete genomePHP domain protein1e-96352
NC_009381:1205900:122558412255841226321738Yersinia pestis Pestoides F chromosome, complete genomeputative hydrolase1e-96352
NC_009708:2347350:236583623658362366573738Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehydrolase1e-96352
NC_014029:2285323:230505923050592305796738Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-96352
NC_017168:3433804:345336734533673454104738Yersinia pestis A1122 chromosome, complete genomeputative hydrolase1e-96352
NC_017265:2213500:223273522327352233472738Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative zinc-binding hydrolase1e-96352
NC_016816:2782373:279550227955022796239738Pantoea ananatis LMG 5342, complete genomePHP domain-containing protein2e-93341
NC_009092:1599526:163408416340841634827744Shewanella loihica PV-4, complete genomePHP C-terminal domain protein5e-80297
NC_017160:2212806:223280222328022233296495Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-71267
NC_009778:2227627:227269522726952273147453Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein5e-66250
NC_017047:1796000:179974817997481800167420Rahnella aquatilis HX2 chromosome, complete genomeputative hydrolase1e-54212
NC_014633:339181:348500348500349249750Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequencePHP domain-containing protein1e-46186
NC_016894:2931213:295346229534622954217756Acetobacterium woodii DSM 1030 chromosome, complete genomeputative hydrolase2e-43175
NC_009778:2227627:223686522368652237239375Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-30133
NC_013517:3997448:401771140177114018442732Sebaldella termitidis ATCC 33386, complete genomePHP domain protein4e-28125
NC_017047:1796000:181092118109211811355435Rahnella aquatilis HX2 chromosome, complete genomeputative hydrolase2e-26119
NC_010001:69000:891228912289832711Clostridium phytofermentans ISDg, complete genomePHP domain protein1e-23110
NC_016816:2782373:278885227888522789136285Pantoea ananatis LMG 5342, complete genomehypothetical protein7e-1994.4
NC_013216:4097056:411783341178334118570738Desulfotomaculum acetoxidans DSM 771, complete genomePHP domain protein3e-1375.5
NC_003551:154883:165843165843166553711Methanopyrus kandleri AV19, complete genomePredicted phosphatase of the PHP family2e-1273.2
NC_004557:2677155:269319926931992693960762Clostridium tetani E88, complete genomeputative DNA polymerase beta3e-1272
NC_009662:1285826:1304084130408413057991716Nitratiruptor sp. SB155-2, complete genomefamily X DNA polymerase IV1e-0860.1
NC_016831:947281:98985298985298994089Salmonella enterica subsp. enterica serovar Gallinarum/pullorum3e-0858.9
NC_011274:2044000:20445262044526204461590Salmonella enterica subsp. enterica serovar Gallinarum str. 287/913e-0858.9