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Query: NC_008150:1593500 Yersinia pestis Antiqua, complete genome

Start: 1593500, End: 1615599, Length: 22100

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_004088:2491303*2491303251808626784Yersinia pestis KIM, complete genome017770BLASTN svgBLASTP svg
NC_003143:2309500*2309500232898119482Yersinia pestis CO92, complete genome017770BLASTN svgBLASTP svg
NC_005810:2091930*2091930210959917670Yersinia pestis biovar Microtus str. 91001, complete genome017760BLASTN svgBLASTP svg
NC_008149:1718000*1718000173562917630Yersinia pestis Nepal516, complete genome017760BLASTN svgBLASTP svg
NC_010465:2383219*2383219240542422206Yersinia pseudotuberculosis YPIII, complete genome016250BLASTN svgBLASTP svg
NC_006155:2378526*2378526239794819423Yersinia pseudotuberculosis IP 32953, complete genome014320BLASTN svgBLASTP svg
NC_010634:2297000*2297000231809921100Yersinia pseudotuberculosis PB1/+, complete genome013840BLASTN svgBLASTP svg
NC_010159:2546590*2546590256968123092Yersinia pestis Angola, complete genome012970BLASTN svgBLASTP svg
NC_004547:2810151*2810151283724527095Erwinia carotovora subsp. atroseptica SCRI1043, complete genome1e-57232BLASTN svgBLASTP svg
NC_014562:1772842*1772842180089428053Pantoea vagans C9-1 chromosome, complete genome8e-56226BLASTN svgBLASTP svg
NC_008258:1934479*1934479196306928591Shigella flexneri 5 str. 8401, complete genome1e-51212BLASTN svgBLASTP svg
NC_004088:11968751196875123427537401Yersinia pestis KIM, complete genome2e-44188BLASTN svgBLASTP svg
NC_005810:87267287267291210839437Yersinia pestis biovar Microtus str. 91001, complete genome2e-44188BLASTN svgBLASTP svg
NC_010159:12880001288000132559537596Yersinia pestis Angola, complete genome2e-44188BLASTN svgBLASTP svg
NC_010634:11754041175404121321037807Yersinia pseudotuberculosis PB1/+, complete genome1e-29139BLASTN svgBLASTP svg
NC_006155:11913071191307123066739361Yersinia pseudotuberculosis IP 32953, complete genome1e-29139BLASTN svgBLASTP svg
NC_007384:1320287*1320287134781127525Shigella sonnei Ss046, complete genome1e-26129BLASTN svgBLASTP svg
NC_010634:31557413155741318046024720Yersinia pseudotuberculosis PB1/+, complete genome1e-23119BLASTN svgBLASTP svg
NC_006155:32379903237990326294924960Yersinia pseudotuberculosis IP 32953, complete genome1e-23119BLASTN svgBLASTP svg
NC_005810:3493607*3493607351772924123Yersinia pestis biovar Microtus str. 91001, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_015224:27903727903730366824632Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,7e-1073.8BLASTN svgBLASTP svg
NC_010465:80424980424984108836840Yersinia pseudotuberculosis YPIII, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_010465:4222586*4222586424312420539Yersinia pseudotuberculosis YPIII, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_010159:74181974181976361621798Yersinia pestis Angola, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_008149:3790897*3790897381416023264Yersinia pestis Nepal516, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_003143:41057544105754412910623353Yersinia pestis CO92, complete genome3e-0971.9BLASTN svgBLASTP svg