Pre_GI: BLASTP Hits

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Query: NC_008150:4561633:4574591 Yersinia pestis Antiqua, complete genome

Start: 4574591, End: 4575202, Length: 612

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3982020:398698239869823987593612Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,inner membrane protein associated with acetate transport1e-110398
NC_003143:483395:496354496354496965612Yersinia pestis CO92, complete genomehypothetical protein1e-110398
NC_010159:809663:815654815654816265612Yersinia pestis Angola, complete genomegpr1/fun34/yaaH family protein1e-110398
NC_004088:4116676:412163841216384122249612Yersinia pestis KIM, complete genomehypothetical protein1e-110398
NC_008149:402599:415557415557416168612Yersinia pestis Nepal516, complete genomemembrane protein1e-110398
NC_010465:3958766:396372839637283964339612Yersinia pseudotuberculosis YPIII, complete genomeGPR1/FUN34/yaaH family protein1e-110398
NC_009381:3596000:360207236020723602683612Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein1e-110398
NC_009708:3903598:390856039085603909171612Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-110398
NC_014029:536000:549847549847550458612Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-110398
NC_017154:478000:491998491998492609612Yersinia pestis D106004 chromosome, complete genomehypothetical protein1e-110398
NC_017160:479411:494189494189494800612Yersinia pestis D182038 chromosome, complete genomehypothetical protein1e-110398
NC_017168:601928:606890606890607501612Yersinia pestis A1122 chromosome, complete genomehypothetical protein1e-110398
NC_006155:713174:723664723664724275612Yersinia pseudotuberculosis IP 32953, complete genomeputative regulator; integral membrane protein3e-109393
NC_005810:4224500:422807442280744228664591Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein1e-98358
NC_016902:4081484:410013041001304100696567Escherichia coli KO11FL chromosome, complete genomeGPR1/FUN34/yaaH family protein1e-74278
NC_012947:3753375:377323037732303773796567Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein1e-74278
CP002516:4081484:410013041001304100696567Escherichia coli KO11, complete genomeGPR1/FUN34/yaaH family protein1e-74278
NC_010468:3970995:399180739918073992373567Escherichia coli ATCC 8739, complete genomeGPR1/FUN34/yaaH family protein4e-74277
NC_016612:2223357:222896022289602229526567Klebsiella oxytoca KCTC 1686 chromosome, complete genomehypothetical protein1e-71268
NC_016629:3254000:326082532608253261379555Desulfovibrio africanus str. Walvis Bay chromosome, completeGPR1/FUN34/yaaH family protein3e-69260
NC_015424:2462522:246574924657492466345597Aeromonas veronii B565 chromosome, complete genomeYaaH7e-67253
NC_016602:2854107:286020728602072860800594Vibrio furnissii NCTC 11218 chromosome 1, complete sequencehypothetical protein1e-65249
NC_013456:3011518:301472930147293015319591Vibrio sp. Ex25 chromosome 1, complete genomehypothetical protein7e-63239
NC_011026:1681852:169175916917591692316558Chloroherpeton thalassium ATCC 35110, complete genomeGPR1/FUN34/yaaH family protein2e-59228
NC_013939:492959:494753494753495406654Deferribacter desulfuricans SSM1, complete genomehypothetical protein5e-57220
NC_010001:434803:464091464091464651561Clostridium phytofermentans ISDg, complete genomeGPR1/FUN34/yaaH family protein3e-51201
NC_015216:1941000:194706919470691947647579Methanobacterium sp. AL-21 chromosome, complete genomeGPR1/FUN34/yaaH family protein4e-45181
NC_003552:5402000:542149354214935422074582Methanosarcina acetivorans C2A, complete genomeGPR1/FUN34/yaaH family protein7e-40163
NC_011832:1148859:115340011534001153990591Candidatus Methanosphaerula palustris E1-9c, complete genomeGPR1/FUN34/yaaH family protein1e-37156
NC_017276:2161535:217923821792382179798561Sulfolobus islandicus REY15A chromosome, complete genomeGPR1/FUN34/yaaH family protein1e-27122
NC_017275:2283074:230077723007772301337561Sulfolobus islandicus HVE10/4 chromosome, complete genomeGPR1/FUN34/yaaH family protein1e-27122
NC_012588:2249874:226710822671082267668561Sulfolobus islandicus M.14.25 chromosome, complete genomeGPR1/FUN34/yaaH family protein2e-27122
NC_012632:2352784:237031923703192370879561Sulfolobus islandicus M.16.27 chromosome, complete genomeGPR1/FUN34/yaaH family protein2e-27122
NC_012726:2249831:226736822673682267928561Sulfolobus islandicus M.16.4 chromosome, complete genomeGPR1/FUN34/yaaH family protein2e-27122
NC_013769:2363980:238150123815012382061561Sulfolobus islandicus L.D.8.5 chromosome, complete genomeGPR1/FUN34/yaaH family protein5e-27120
NC_012623:277113:279207279207279767561Sulfolobus islandicus Y.N.15.51 chromosome, complete genomeGPR1/FUN34/yaaH family protein5e-27120
NC_012589:2379709:239842923984292398989561Sulfolobus islandicus L.S.2.15, complete genomeGPR1/FUN34/yaaH family protein5e-27120
NC_007181:1740000:175698417569841757544561Sulfolobus acidocaldarius DSM 639, complete genomehypothetical protein2e-25115
NC_011773:3371989:338068533806853381305621Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-1995.9
NC_014335:3288500:329051532905153291159645Bacillus cereus biovar anthracis str. CI chromosome, completeGPR1/FUN34/YaaH family protein3e-1891.7
NC_012559:1064821:109019510901951090821627Laribacter hongkongensis HLHK9, complete genomehypothetical protein2e-0858.9