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Query: NC_008150:4561633:4571855 Yersinia pestis Antiqua, complete genome

Start: 4571855, End: 4574302, Length: 2448

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3982020:3987882398788239903292448Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein01648
NC_010159:809663:8165548165548190012448Yersinia pestis Angola, complete genomeacetyltransferase, GNAT family domain protein01648
NC_008149:402599:4128224128224152692448Yersinia pestis Nepal516, complete genomehypothetical protein01648
NC_005810:4224500:4228973422897342314202448Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein01648
NC_004088:4116676:4122538412253841249852448Yersinia pestis KIM, complete genomehypothetical protein01648
NC_009381:3596000:3602972360297236054192448Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein01648
NC_014029:536000:5471115471115495582448Yersinia pestis Z176003 chromosome, complete genomehypothetical protein01648
NC_017154:478000:4892624892624917092448Yersinia pestis D106004 chromosome, complete genomehypothetical protein01648
NC_017160:479411:4914534914534939002448Yersinia pestis D182038 chromosome, complete genomehypothetical protein01648
NC_017168:601928:6077906077906102372448Yersinia pestis A1122 chromosome, complete genomehypothetical protein01648
NC_003143:483395:4936184936184960652448Yersinia pestis CO92, complete genomehypothetical protein01648
NC_010465:3958766:3964629396462939670852457Yersinia pseudotuberculosis YPIII, complete genomeGCN5-related N-acetyltransferase01606
NC_006155:713174:7209177209177233732457Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein01541
NC_009708:3903598:3909461390946139119082448Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeacetyltransferase domain-containing protein01435
NC_010634:3269010:3279395327939532818152421Yersinia pseudotuberculosis PB1/+, complete genomebeta and gamma crystallin5e-128459
NC_008150:2599661:2603804260380426062242421Yersinia pestis Antiqua, complete genomehypothetical protein2e-127457
NC_017154:2901300:2905444290544429078642421Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-127457
NC_017168:2560000:2565403256540325678232421Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-127457
NC_010159:409500:4389284389284413482421Yersinia pestis Angola, complete genomehypothetical protein3e-127456
NC_015224:4473230:4483717448371744859062190Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein2e-97357
NC_015224:4473230:4486015448601544881922178Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein9e-93342
NC_015224:4473230:4481654448165444836902037Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein4e-64246