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Query: NC_008150:4373722:4377363 Yersinia pestis Antiqua, complete genome

Start: 4377363, End: 4378517, Length: 1155

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:4065625:4069266406926640704201155Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein0788
NC_008149:318860:3327563327563339101155Yersinia pestis Nepal516, complete genomehypothetical protein0788
NC_003143:398748:4135484135484147021155Yersinia pestis CO92, complete genomehypothetical protein0788
NC_004088:4202247:4205888420588842070421155Yersinia pestis KIM, complete genomehypothetical protein0788
NC_009381:3680638:3684301368430136854551155Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0788
NC_014029:452248:4670484670484682021155Yersinia pestis Z176003 chromosome, complete genomehypothetical protein0788
NC_017154:394401:4092004092004103541155Yersinia pestis D106004 chromosome, complete genomehypothetical protein0788
NC_017160:396600:4114004114004125541155Yersinia pestis D182038 chromosome, complete genomehypothetical protein0788
NC_017168:687471:6911126911126922661155Yersinia pestis A1122 chromosome, complete genomehypothetical protein0788
NC_005810:4306716:4310357431035743115111155Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0785
NC_008463:282565:2972222972222983671146Pseudomonas aeruginosa UCBPP-PA14, complete genomehypothetical protein1e-145516
NC_002947:4167500:4212569421256942137201152Pseudomonas putida KT2440, complete genomehypothetical protein2e-108392
NC_014500:3097362:3117730311773031189231194Dickeya dadantii 3937 chromosome, complete genomehypothetical protein5e-36152
NC_007759:1666967:1683347168334716845221176Syntrophus aciditrophicus SB, complete genomehypothetical cytosolic protein1e-1687.8
NC_009614:4528418:4535109453510945362751167Bacteroides vulgatus ATCC 8482 chromosome, complete genomehypothetical protein7e-1478.6
NC_010545:1475410:1497196149719614983111116Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein3e-1169.7
NC_015172:775128:7926177926177937951179Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomehypothetical protein1e-1067.8
NC_007498:2087811:2115749211574921169241176Pelobacter carbinolicus DSM 2380, complete genomehypothetical protein2e-0963.9
NC_012590:1950154:1955675195567519568111137Corynebacterium aurimucosum ATCC 700975, complete genomehypothetical protein2e-0963.5
NC_008269:1067082:1065913106591310670851173Rhodococcus sp. RHA1 plasmid pRHL1, complete sequencehypothetical protein1e-0654.3