Some Help

Query: NC_008150:2599661:2599661 Yersinia pestis Antiqua, complete genome

Start: 2599661, End: 2600698, Length: 1038

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:2560000:2561260256126025622971038Yersinia pestis A1122 chromosome, complete genomecytoskeletal protein RodZ5e-175613
NC_010159:409500:4347854347854358221038Yersinia pestis Angola, complete genomehypothetical protein5e-175613
NC_017154:2901300:290130029013002902289990Yersinia pestis D106004 chromosome, complete genomeDNA-binding protein2e-165582
NC_010634:3269010:3275201327520132762891089Yersinia pseudotuberculosis PB1/+, complete genomeXRE family transcriptional regulator9e-163573
NC_011601:2854178:2877260287726028782671008Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomecytoskeletal protein RodZ1e-92340
NC_016893:181951:190112190112190609498Wigglesworthia glossinidia endosymbiont of Glossina morsitansputative DNA-binding protein1e-1894.4
NC_004344:622318:641232641232641708477Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein5e-1789
NC_015222:1127675:1136550113655011377761227Nitrosomonas sp. AL212 chromosome, complete genometranscriptional regulator, XRE family1e-0757.4