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Query: NC_008150:2207198:2221327 Yersinia pestis Antiqua, complete genome

Start: 2221327, End: 2221836, Length: 510

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1571305:160306116030611603570510Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein5e-96349
NC_010634:2894631:290057429005742901083510Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein5e-96349
NC_004088:1851500:188198018819801882489510Yersinia pestis KIM, complete genomehypothetical protein5e-96349
NC_010159:1794000:180365318036531804162510Yersinia pestis Angola, complete genomehypothetical protein5e-96349
NC_008149:2337336:235146523514652351974510Yersinia pestis Nepal516, complete genomehypothetical protein5e-96349
NC_006155:2979500:298264429826442983153510Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein5e-96349
NC_009381:2138625:214181821418182142327510Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein5e-96349
NC_014029:2729832:274193427419342742443510Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-96349
NC_017154:2774955:278908427890842789593510Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-96349
NC_017160:2787637:281945028194502819959510Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-96349
NC_017168:2941938:297231529723152972824510Yersinia pestis A1122 chromosome, complete genomehypothetical protein5e-96349
NC_003143:2778494:278961227896122790115504Yersinia pestis CO92, complete genomehypothetical protein8e-95345
NC_014306:2476316:248836824883682488877510Erwinia billingiae Eb661, complete genomeconserved uncharacterized protein6e-35146
NC_004578:3597083:360813636081363608651516Pseudomonas syringae pv. tomato str. DC3000, complete genomehypothetical protein9e-31132
NC_013283:113660:126026126026126508483Cronobacter turicensis plasmid pCTU1, complete sequencehypothetical protein2e-29127
NC_011145:4365730:437817343781734378658486Anaeromyxobacter sp. K, complete genomehypothetical protein4e-1787.4
NC_008095:6253610:627020762702076270671465Myxococcus xanthus DK 1622, complete genomehypothetical protein1e-1582.8