Some Help

Query: NC_008150:2207198:2217927 Yersinia pestis Antiqua, complete genome

Start: 2217927, End: 2218124, Length: 198

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1571305:160677316067731606970198Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein2e-30131
NC_017168:2941938:297602729760272976224198Yersinia pestis A1122 chromosome, complete genomehypothetical protein2e-30131
NC_003143:2778494:278621227862122786409198Yersinia pestis CO92, complete genomehypothetical protein2e-30131
NC_010159:1794000:180024718002471800444198Yersinia pestis Angola, complete genomehypothetical protein2e-30131
NC_005810:2549680:255584025558402556037198Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-30131
NC_008149:2337336:234806523480652348262198Yersinia pestis Nepal516, complete genomehypothetical protein2e-30131
NC_004088:1851500:188569218856921885889198Yersinia pestis KIM, complete genomehypothetical protein2e-30131