Pre_GI: BLASTP Hits

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Query: NC_008150:2207198:2210209 Yersinia pestis Antiqua, complete genome

Start: 2210209, End: 2211495, Length: 1287

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017154:2774955:2777966277796627792521287Yersinia pestis D106004 chromosome, complete genomeputative solute-binding protein0872
NC_008149:2337336:2340347234034723416331287Yersinia pestis Nepal516, complete genomesolute-binding protein0872
NC_010465:1790739:1811394181139418126801287Yersinia pseudotuberculosis YPIII, complete genomeextracellular solute-binding protein family 10872
NC_003143:2778494:2778494277849427797801287Yersinia pestis CO92, complete genomeputative solute-binding protein0872
NC_009708:1735903:1776767177676717780531287Yersinia pseudotuberculosis IP 31758 chromosome, complete genomecarbohydrate ABC transporter periplasmic-binding protein0872
NC_014029:2729832:2730816273081627321021287Yersinia pestis Z176003 chromosome, complete genomeputative solute-binding protein0872
NC_017095:1757935:1774531177453117757811251Fervidobacterium pennivorans DSM 9078 chromosome, complete genomecarbohydrate ABC transporter substrate-binding protein3e-99362
NC_015958:57957:7393973939752641326Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomefamily 1 extracellular solute-binding protein1e-63244
NC_014376:3214222:3234910323491032363641455Clostridium saccharolyticum WM1 chromosome, complete genomesugar ABC transporter3e-47189
NC_013172:542896:5636415636415649691329Brachybacterium faecium DSM 4810, complete genomeABC-type sugar transport system, periplasmic component4e-25116
NC_016641:1984206:1986876198687619881261251Paenibacillus terrae HPL-003 chromosome, complete genomesugar ABC transporter periplasmic protein1e-1584.3
NC_006322:2886404:2908934290893429102381305Bacillus licheniformis ATCC 14580, complete genomeAraN1e-0965.1
NC_020291:1045058:1051597105159710528561260Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeextracellular solute-binding protein, family 11e-0964.7
NC_020291:6310000:6326586632658663278271242Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeABC-type sugar transport system, periplasmic component4e-0962.8
NC_013526:105195:1229431229431243491407Thermobaculum terrenum ATCC BAA-798 chromosome 2, complete genomeextracellular solute-binding protein family 12e-0860.8
NC_014364:815346:8385568385568398301275Spirochaeta smaragdinae DSM 11293 chromosome, complete genomeextracellular solute-binding protein family 12e-0757
NC_013656:2317224:2320566232056623218101245Lactococcus lactis subsp. lactis KF147, complete genomesugar ABC transporter sugar-binding protein7e-0755.5
NC_013850:4829455:4856074485607448573841311Klebsiella variicola At-22 chromosome, complete genomeextracellular solute-binding protein family 12e-0654.3
NC_011283:5011497:5033154503315450344641311Klebsiella pneumoniae 342 chromosome, complete genomeABC transporter substrate-binding protein2e-0653.9
NC_014246:1787154:1798378179837817996131236Mobiluncus curtisii ATCC 43063 chromosome, complete genomesugar ABC transporter substrate-binding protein2e-0653.9
NC_013521:302574:3359023359023371611260Sanguibacter keddieii DSM 10542, complete genomeABC-type sugar transport system, periplasmic component2e-0653.9
NC_016641:4653889:4669035466903546702971263Paenibacillus terrae HPL-003 chromosome, complete genomefamily 1 extracellular solute-binding protein9e-0652