Pre_GI: BLASTP Hits

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Query: NC_008150:2173708:2193779 Yersinia pestis Antiqua, complete genome

Start: 2193779, End: 2194729, Length: 951

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017168:2999514:299951429995143000464951Yersinia pestis A1122 chromosome, complete genomehypothetical protein0655
NC_005810:2508671:253189325318932532843951Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein0655
NC_003143:2741478:276196927619692762919951Yersinia pestis CO92, complete genomehypothetical protein0655
NC_013421:4006085:402109340210934022025933Pectobacterium wasabiae WPP163, complete genomeCRISPR-associated protein, Csy2 family4e-105381
NC_016818:1963875:196846819684681969421954Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completeCRISPR type I-F/YPEST-associated protein Csy23e-100365
NC_014836:993448:998811998811999797987Desulfurispirillum indicum S5 chromosome, complete genomeCsy2 family CRISPR-associated protein3e-89328
NC_014216:1787000:179368517936851794644960Desulfurivibrio alkaliphilus AHT2 chromosome, complete genomeCRISPR-associated protein, Csy2 family1e-80300
NC_014532:110875:124000124000124959960Halomonas elongata DSM 2581, complete genomehypothetical protein3e-49195
NC_013889:2561381:257257825725782573546969Thioalkalivibrio sp. K90mix chromosome, complete genomeCRISPR-associated protein, Csy2 family8e-48191
NC_012796:4693500:4728304472830447293111008Desulfovibrio magneticus RS-1, complete genomehypothetical protein5e-46184
NC_018145:683874:6953056953056963181014Zymomonas mobilis subsp. mobilis ATCC 29191 chromosome, completeCRISPR-associated protein, Csy2 family8e-43174
NC_015436:1322087:132371413237141324607894Spirochaeta coccoides DSM 17374 chromosome, complete genomeCRISPR-associated protein, Csy2 family2e-35149
NC_009446:174951:176243176243177193951Dichelobacter nodosus VCS1703A, complete genomehypothetical protein6e-35148
NC_015873:1933036:194566619456661946553888Megasphaera elsdenii DSM 20460, complete genomeCRISPR-associated protein4e-29129
NC_017098:477000:487858487858488745888Spirochaeta africana DSM 8902 chromosome, complete genomeCRISPR type I-F/YPEST-associated protein Csy24e-27122
NC_020418:3022891:303006530300653030886822Morganella morganii subsp. morganii KT, complete genomeCRISPR-associated protein, Csy2 family3e-24112