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Query: NC_008150:1384102:1398322 Yersinia pestis Antiqua, complete genome

Start: 1398322, End: 1398407, Length: 86

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2306500:23216822321682232176786Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,tRNA-Leu6e-0959.7
NC_008149:2517538:25366272536627253671286Yersinia pestis Nepal516, complete genometRNA-Leu6e-0959.7
NC_003143:2101902:21152432115243211532886Yersinia pestis CO92, complete genometRNA-Leu6e-0959.7
NC_015224:2061951:20784682078468207855386Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,tRNA-Leu6e-0959.7
NC_010465:2582080:25870742587074258715986Yersinia pseudotuberculosis YPIII, complete genometRNA-Leu6e-0959.7
NC_006155:2084669:20968692096869209695486Yersinia pseudotuberculosis IP 32953, complete genometRNA-Leu6e-0959.7
NC_005810:1663672:16739731673973167405886Yersinia pestis biovar Microtus str. 91001, complete genometRNA-Leu6e-0959.7
NC_010159:2128157:21422872142287214237286Yersinia pestis Angola, complete genometRNA-Leu6e-0959.7
NC_008800:2013450:20134502013450201353586Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,tRNA-Leu6e-0959.7
NC_017168:3535786:35456853545685354577086Yersinia pestis A1122 chromosome, complete genometRNA-Leu6e-0959.7
NC_017160:2414000:24237432423743242382886Yersinia pestis D182038 chromosome, complete genometRNA-Leu6e-0959.7
NC_017154:2100587:21147852114785211487086Yersinia pestis D106004 chromosome, complete genometRNA-Leu6e-0959.7
NC_014029:2388500:23947362394736239482186Yersinia pestis Z176003 chromosome, complete genometRNA-Leu6e-0959.7
NC_009708:2537557:25571092557109255719486Yersinia pseudotuberculosis IP 31758 chromosome, complete genometRNA-Leu6e-0959.7
NC_009381:1414985:14208571420857142094286Yersinia pestis Pestoides F chromosome, complete genometRNA-Leu6e-0959.7
NC_020064:1854589:18632891863289186337486Serratia marcescens FGI94, complete genometRNA-Leu2e-0858.2
NC_015566:1941407:19517901951790195187586Serratia sp. AS12 chromosome, complete genometRNA-Leu2e-0858.2
NC_004088:2691565:27015032701503270158583Yersinia pestis KIM, complete genometRNA-Leu4e-0856.6
NC_007712:1954808:19738091973809197389486Sodalis glossinidius str. 'morsitans', complete genometRNA-Leu1e-0651.6