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Query: NC_008150:1384102:1398238 Yersinia pestis Antiqua, complete genome

Start: 1398238, End: 1398311, Length: 74

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2306500:23217782321778232185174Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,tRNA-Cys5e-0753.1
NC_005810:1663672:16740691674069167414274Yersinia pestis biovar Microtus str. 91001, complete genometRNA-Cys5e-0753.1
NC_008149:2517538:25367232536723253679674Yersinia pestis Nepal516, complete genometRNA-Cys5e-0753.1
NC_006155:2084669:20967852096785209685874Yersinia pseudotuberculosis IP 32953, complete genometRNA-Cys5e-0753.1
NC_010465:2582080:25871702587170258724374Yersinia pseudotuberculosis YPIII, complete genometRNA-Cys5e-0753.1
NC_015224:2061951:20783842078384207845774Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,tRNA-Cys5e-0753.1
NC_003143:2101902:21151592115159211523274Yersinia pestis CO92, complete genometRNA-Cys5e-0753.1
NC_008800:2013450:20135462013546201361974Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,tRNA-Cys5e-0753.1
NC_009381:1414985:14209531420953142102674Yersinia pestis Pestoides F chromosome, complete genometRNA-Cys5e-0753.1
NC_014029:2388500:23948322394832239490574Yersinia pestis Z176003 chromosome, complete genometRNA-Cys5e-0753.1
NC_017154:2100587:21147012114701211477474Yersinia pestis D106004 chromosome, complete genometRNA-Cys5e-0753.1
NC_017160:2414000:24238392423839242391274Yersinia pestis D182038 chromosome, complete genometRNA-Cys5e-0753.1
NC_017168:3535786:35457813545781354585474Yersinia pestis A1122 chromosome, complete genometRNA-Cys5e-0753.1
NC_004088:2691565:27015992701599270166971Yersinia pestis KIM, complete genometRNA-Cys1e-0651.6
NC_007712:1954808:19737191973719197379274Sodalis glossinidius str. 'morsitans', complete genometRNA-Cys3e-0650.4