Pre_GI: BLASTP Hits

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Query: NC_008150:1384102:1393521 Yersinia pestis Antiqua, complete genome

Start: 1393521, End: 1393865, Length: 345

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from the Republic of Congo. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017160:2414000:242828424282842428628345Yersinia pestis D182038 chromosome, complete genomehypothetical protein4e-58223
NC_010159:2128157:213748621374862137830345Yersinia pestis Angola, complete genomeGlpM protein4e-58223
NC_004088:2691565:270604227060422706386345Yersinia pestis KIM, complete genomehypothetical protein4e-58223
NC_006155:2084669:209206820920682092412345Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein4e-58223
NC_005810:1663672:167851516785151678859345Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-58223
NC_009381:1414985:142539914253991425743345Yersinia pestis Pestoides F chromosome, complete genomemembrane protein4e-58223
NC_014029:2388500:239927823992782399622345Yersinia pestis Z176003 chromosome, complete genomehypothetical protein4e-58223
NC_017154:2100587:210998421099842110328345Yersinia pestis D106004 chromosome, complete genomehypothetical protein4e-58223
NC_003143:2101902:211044221104422110783342Yersinia pestis CO92, complete genomehypothetical protein1e-57221
NC_010465:2582080:259161925916192591960342Yersinia pseudotuberculosis YPIII, complete genomeGlpM family protein1e-57221
NC_009708:2537557:256165525616552561996342Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeGlpM protein1e-57221
NC_017168:3535786:355023035502303550571342Yersinia pestis A1122 chromosome, complete genomeGlpM family protein1e-57221
NC_015224:2061951:207365820736582073996339Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,hypothetical protein7e-47185
NC_008800:2013450:201800620180062018344339Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein3e-45180
NC_015061:2770856:279062627906262790967342Rahnella sp. Y9602 chromosome, complete genomeGlpM family protein2e-39160
NC_015566:1941407:194687419468741947215342Serratia sp. AS12 chromosome, complete genomeGlpM family protein2e-38157
NC_013592:2703327:272326727232672723608342Dickeya dadantii Ech586, complete genomeGlpM family protein8e-35145
NC_012912:2800884:281787928178792818220342Dickeya zeae Ech1591, complete genomeGlpM family protein2e-34144
NC_012880:2778795:279265627926562793000345Dickeya dadantii Ech703, complete genomeGlpM family protein3e-30130
NC_006138:656000:663064663064663411348Desulfotalea psychrophila LSv54, complete genomemembrane protein GlpM3e-22103
NC_013508:2130681:216081421608142161143330Edwardsiella tarda EIB202, complete genomehypothetical protein2e-2097.8
NC_012779:2184927:218839521883952188583189Edwardsiella ictaluri 93-146, complete genomemembrane protein GlpM9e-1062.4