Pre_GI: BLASTN Hits

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Query: NC_008149:3022970 Yersinia pestis Nepal516, complete genome

Start: 3022970, End: 3045599, Length: 22630

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_004088:31869543186954320951322560Yersinia pestis KIM, complete genome027580BLASTN svgBLASTP svg
NC_005810:14133051413305143757924275Yersinia pestis biovar Microtus str. 91001, complete genome027270BLASTN svgBLASTP svg
NC_010465:30469043046904306991523012Yersinia pseudotuberculosis YPIII, complete genome026660BLASTN svgBLASTP svg
NC_003143:14412111441211146223121021Yersinia pestis CO92, complete genome021670BLASTN svgBLASTP svg
NC_010159:15580001558000157786119862Yersinia pestis Angola, complete genome021650BLASTN svgBLASTP svg
NC_006155:15673061567306159029622991Yersinia pseudotuberculosis IP 32953, complete genome020980BLASTN svgBLASTP svg
NC_010634:15657881565788158879323006Yersinia pseudotuberculosis PB1/+, complete genome020890BLASTN svgBLASTP svg
NC_008150:11478831147883116687718995Yersinia pestis Antiqua, complete genome016640BLASTN svgBLASTP svg
NC_014121:35538093553809358001526207Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete9e-71276BLASTN svgBLASTP svg
NC_012880:10914861091486111695125466Dickeya dadantii Ech703, complete genome1e-26129BLASTN svgBLASTP svg
CP002797:46563274656327468071624390Escherichia coli NA114, complete genome8e-25123BLASTN svgBLASTP svg
NC_007946:48759974875997491969643700Escherichia coli UTI89, complete genome1e-23119BLASTN svgBLASTP svg
NC_004431:51233255123325514909025766Escherichia coli CFT073, complete genome1e-23119BLASTN svgBLASTP svg
NC_011750:49780004978000500028022281Escherichia coli IAI39 chromosome, complete genome2e-22115BLASTN svgBLASTP svg
NC_008253:48178644817864486276044897Escherichia coli 536, complete genome3e-21111BLASTN svgBLASTP svg
NC_007613:44030704403070442929526226Shigella boydii Sb227, complete genome3e-21111BLASTN svgBLASTP svg
NC_000913:45282784528278455238424107Escherichia coli K12, complete genome3e-21111BLASTN svgBLASTP svg
CU928160:4570498*4570498461509944602Escherichia coli IAI1 chromosome, complete genome3e-21111BLASTN svgBLASTP svg
CP002185:47918114791811481779025980Escherichia coli W, complete genome3e-21111BLASTN svgBLASTP svg
AC_000091:45349354534935455904124107Escherichia coli W3110 DNA, complete genome3e-21111BLASTN svgBLASTP svg
CP002185:17274931727493175122423732Escherichia coli W, complete genome7e-1073.8BLASTN svgBLASTP svg
CU928160:16255351625535164926623732Escherichia coli IAI1 chromosome, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_000913:1625500*1625500165193926440Escherichia coli K12, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_002655:19091391909139193312123983Escherichia coli O157:H7 EDL933, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_008563:16512701651270167412522856Escherichia coli APEC O1, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_010473:1712984*1712984174109928116Escherichia coli str. K-12 substr. DH10B, complete genome7e-1073.8BLASTN svgBLASTP svg
AC_000091:16270491627049165562928581Escherichia coli W3110 DNA, complete genome7e-1073.8BLASTN svgBLASTP svg