Pre_GI: BLASTP Hits

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Query: NC_008149:3790897:3809786 Yersinia pestis Nepal516, complete genome

Start: 3809786, End: 3810100, Length: 315

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005810:515744:516539516539516856318Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein8e-57218
NC_010159:741819:759224759224759538315Yersinia pestis Angola, complete genomeL-rhamnose 1-epimerase8e-57218
NC_006155:456000:457114457114457428315Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein8e-57218
NC_009381:4169353:418821841882184188532315Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein8e-57218
NC_009708:4215500:423483442348344235148315Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeL-rhamnose 1-epimerase8e-57218
NC_014029:331919:331919331919332233315Yersinia pestis Z176003 chromosome, complete genomehypothetical protein8e-57218
NC_017154:331921:331921331921332235315Yersinia pestis D106004 chromosome, complete genomehypothetical protein8e-57218
NC_017168:751078:769967769967770281315Yersinia pestis A1122 chromosome, complete genomeL-rhamnose 1-epimerase8e-57218
NC_017265:644384:661103661103661417315Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,L-rhamnose mutarotase8e-57218
NC_010465:4222586:423869542386954239009315Yersinia pseudotuberculosis YPIII, complete genomeL-rhamnose 1-epimerase8e-57218
NC_012912:4071859:409434540943454094659315Dickeya zeae Ech1591, complete genomeL-rhamnose 1-epimerase6e-41166
NC_020063:4653422:465945246594524659766315Enterobacteriaceae bacterium strain FGI 57, complete genomeL-rhamnose 1-epimerase5e-40162
NC_014650:3438466:344583434458343446148315Geobacillus sp. Y4.1MC1 chromosome, complete genomeL-rhamnose 1-epimerase3e-30130
NC_015660:3467579:347747334774733477787315Geobacillus thermoglucosidasius C56-YS93 chromosome, completeL-rhamnose 1-epimerase3e-30130
NC_004193:375416:524067524067524381315Oceanobacillus iheyensis HTE831, complete genomehypothetical protein5e-30129
NC_014655:2581968:258862925886292588943315Leadbetterella byssophila DSM 17132 chromosome, complete genomel-rhamnose 1-epimerase1e-21101
NC_015177:4478986:449113144911314491439309Pedobacter saltans DSM 12145 chromosome, complete genomeL-rhamnose 1-epimerase8e-2095.5
NC_014210:2747787:274881127488112749128318Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,protein of unknown function DUF7185e-0959.7
NC_015957:3342169:335895833589583359278321Streptomyces violaceusniger Tu 4113 chromosome, complete genomehypothetical protein2e-0754.3
NC_013093:1036772:108726010872601087580321Actinosynnema mirum DSM 43827, complete genomeprotein of unknown function DUF7181e-0652