Pre_GI: BLASTP Hits

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Query: NC_008149:3790897:3807733 Yersinia pestis Nepal516, complete genome

Start: 3807733, End: 3808557, Length: 825

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:644384:659050659050659874825Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,rhamnulose-1-phosphate aldolase9e-162569
NC_005810:515744:518082518082518906825Yersinia pestis biovar Microtus str. 91001, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_010159:741819:757171757171757995825Yersinia pestis Angola, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_010465:4222586:423664242366424237466825Yersinia pseudotuberculosis YPIII, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_009381:4169353:418616541861654186989825Yersinia pestis Pestoides F chromosome, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_014029:331919:333462333462334286825Yersinia pestis Z176003 chromosome, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_017154:331921:333464333464334288825Yersinia pestis D106004 chromosome, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_017168:751078:767914767914768738825Yersinia pestis A1122 chromosome, complete genomerhamnulose-1-phosphate aldolase9e-162569
NC_009708:4215500:423278142327814233605825Yersinia pseudotuberculosis IP 31758 chromosome, complete genomerhamnulose-1-phosphate aldolase8e-161566
NC_006155:456000:458657458657459481825Yersinia pseudotuberculosis IP 32953, complete genomerhamnulose-1-phosphate aldolase8e-161566
NC_012912:4071859:409329840932984094128831Dickeya zeae Ech1591, complete genomerhamnulose-1-phosphate aldolase3e-128457
NC_020063:4653422:465741346574134658237825Enterobacteriaceae bacterium strain FGI 57, complete genomeL-rhamnulose 1-phosphate aldolase1e-109396
NC_004193:375416:375416375416675301299886Oceanobacillus iheyensis HTE831, complete genome5e-78291
NC_004193:375416:528632528632529468837Oceanobacillus iheyensis HTE831, complete genomerhamnulose-1-phosphate aldolase1e-75283
NC_014650:3438466:344618134461813447014834Geobacillus sp. Y4.1MC1 chromosome, complete genomerhamnulose-1-phosphate aldolase3e-75281
NC_015660:3467579:347782034778203478653834Geobacillus thermoglucosidasius C56-YS93 chromosome, completerhamnulose-1-phosphate aldolase3e-75281
NC_014622:5553628:557123555712355572080846Paenibacillus polymyxa SC2 chromosome, complete genomerhamnulose-1-phosphate aldolase9e-70263
NC_007930:21793:217932179322608816Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,Rhamnulose-1-phosphate aldolase3e-63241
NC_015389:616430:647583647583648428846Coriobacterium glomerans PW2 chromosome, complete genomeL-rhamnulose 1-phosphate aldolase4e-51201
NC_015514:3351052:336440533644053365232828Cellulomonas fimi ATCC 484 chromosome, complete genomeRhamnulose-1-phosphate aldolase4e-1892
NC_000853:1071078:108745310874531088163711Thermotoga maritima MSB8, complete genomerhamnulose-1-phosphate aldolase5e-1891.7
NC_010939:1920781:194387119438711944521651Actinobacillus pleuropneumoniae serovar 7 str. AP76, completeL-fuculose phosphate aldolase1e-0654.3
NC_009053:1895485:191790619179061918556651Actinobacillus pleuropneumoniae L20, complete genomeL-fuculose phosphate aldolase1e-0654.3