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Query: NC_008149:3790897:3806464 Yersinia pestis Nepal516, complete genome

Start: 3806464, End: 3807720, Length: 1257

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:644384:6577816577816590371257Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,L-rhamnose isomerase0864
NC_017168:751078:7666457666457679011257Yersinia pestis A1122 chromosome, complete genomeL-rhamnose isomerase0864
NC_014029:331919:3342993342993355551257Yersinia pestis Z176003 chromosome, complete genomeL-rhamnose isomerase0864
NC_009381:4169353:4184896418489641861521257Yersinia pestis Pestoides F chromosome, complete genomeL-rhamnose isomerase0864
NC_010465:4222586:4235373423537342366291257Yersinia pseudotuberculosis YPIII, complete genomeL-rhamnose isomerase0864
NC_010159:741819:7559027559027571581257Yersinia pestis Angola, complete genomeL-rhamnose isomerase0864
NC_009708:4215500:4231512423151242327681257Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeL-rhamnose isomerase0863
NC_005810:515744:5189195189195201811263Yersinia pestis biovar Microtus str. 91001, complete genomeL-rhamnose isomerase0863
NC_006155:456000:4594944594944607501257Yersinia pseudotuberculosis IP 32953, complete genomeL-rhamnose isomerase0860
NC_017154:331921:3343443343443355581215Yersinia pestis D106004 chromosome, complete genomeL-rhamnose isomerase0830
NC_020063:4653422:4656025465602546572841260Enterobacteriaceae bacterium strain FGI 57, complete genomeL-rhamnose isomerase0755
NC_012912:4071859:4092018409201840932741257Dickeya zeae Ech1591, complete genomeL-rhamnose isomerase0711
NC_014650:3438466:3447026344702634482881263Geobacillus sp. Y4.1MC1 chromosome, complete genomeL-rhamnose isomerase3e-156551
NC_015660:3467579:3478665347866534799271263Geobacillus thermoglucosidasius C56-YS93 chromosome, completeL-rhamnose isomerase3e-156551
NC_014622:5553628:5569926556992655711821257Paenibacillus polymyxa SC2 chromosome, complete genomeL-rhamnose isomerase rhaa4e-152538
NC_004193:375416:5273435273435285961254Oceanobacillus iheyensis HTE831, complete genomeL-rhamnose isomerase1e-146519
NC_015389:616430:6462596462596475181260Coriobacterium glomerans PW2 chromosome, complete genomeL-rhamnose isomerase1e-109397