Some Help

Query: NC_008149:1221637:1241412 Yersinia pestis Nepal516, complete genome

Start: 1241412, End: 1242029, Length: 618

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Isolated from a soil sample from Nepal. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:1291754:131151113115111312128618Yersinia pestis KIM, complete genomeregulatory protein1e-114412
NC_003143:2895617:291536029153602915977618Yersinia pestis CO92, complete genomeputative LuxR-family regulatory proteins1e-114412
NC_008150:2785830:279490227949022795519618Yersinia pestis Antiqua, complete genomeputative LuxR-family regulatory proteins1e-114412
NC_017154:3094000:309402230940223094612591Yersinia pestis D106004 chromosome, complete genomeLuxR family transcriptional regulator6e-109392
NC_008800:3279468:328391932839193284530612Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,LuxR family regulatory protein1e-102372
NC_015224:1440283:145346614534661454056591Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,LuxR family regulatory protein2e-97354
NC_012721:182965:206066206066206713648Burkholderia glumae BGR1 chromosome 2, complete genomeResponse regulator9e-0857
NC_015382:172213:182580182580183332753Burkholderia gladioli BSR3 plasmid bgla_1p, complete sequencetwo component LuxR family transcriptional regulator8e-0857
NC_009076:2050621:207363120736312074296666Burkholderia pseudomallei 1106a chromosome I, complete sequenceDNA-binding response regulator, LuxR family4e-0754.7
NC_007435:1981164:199033219903321990994663Burkholderia pseudomallei 1710b chromosome II, complete sequenceDNA-binding response regulator6e-0753.9
NC_009078:142794:151961151961152623663Burkholderia pseudomallei 1106a chromosome II, complete sequenceDNA-binding response regulator, LuxR family6e-0753.9
NC_006351:142788:151956151956152618663Burkholderia pseudomallei K96243 chromosome 2, complete sequencetwo-component system response regulator6e-0753.9
NC_012660:1737423:176364217636421764289648Pseudomonas fluorescens SBW25 chromosome, complete genomeputative two-component system LuxR family response regulator2e-0652.8
NC_014117:2684631:269515426951542695861708Burkholderia sp. CCGE1002 chromosome chromosome 1, completetwo component transcriptional regulator, LuxR family3e-0652