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Query: NC_007797:411630 Anaplasma phagocytophilum HZ, complete genome

Start: 411630, End: 431601, Length: 19972

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_006833:1011537*1011537105506743531Wolbachia endosymbiont strain TRS of Brugia malayi, complete1e-1489.7BLASTN svgBLASTP svg
NC_005295:845000*84500086826523266Ehrlichia ruminantium str. Welgevonden, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_006832:825000*82500084423819239Ehrlichia ruminantium str. Welgevonden, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_006831:821000*82100084424623247Ehrlichia ruminantium str. Gardel, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_009879:57500*575007654419045Rickettsia canadensis str. McKiel, complete genome6e-0763.9BLASTN svgBLASTP svg