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Query: NC_007797:692944:697597 Anaplasma phagocytophilum HZ, complete genome

Start: 697597, End: 698037, Length: 441

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003103:266013:267791267791268291501Rickettsia conorii str. Malish 7, complete genomeco-chaperone HscB2e-0961.6
NC_007109:1105251:112375411237541124254501Rickettsia felis URRWXCal2, complete genomeco-chaperone HscB2e-0961.2
NC_017154:2901300:292252929225292923053525Yersinia pestis D106004 chromosome, complete genomeco-chaperone HscB3e-0960.8
NC_008150:2599661:262088926208892621413525Yersinia pestis Antiqua, complete genomechaperone protein HscB3e-0960.8
NC_012559:2752825:276876827687682769283516Laribacter hongkongensis HLHK9, complete genomehypothetical protein3e-0754.3
NC_017517:1377617:139426313942631394763501Neisseria meningitidis M01-240355 chromosome, complete genomeFe-S protein assembly co-chaperone HscB2e-0651.2
NC_003116:1488576:150390515039051504405501Neisseria meningitidis Z2491, complete genomechaperone protein2e-0651.2
NC_017512:1264542:127987112798711280371501Neisseria meningitidis WUE 2594, complete genomeco-chaperone protein Hsc202e-0651.2
NC_017505:1338661:135602413560241356524501Neisseria meningitidis alpha710 chromosome, complete genomechaperone protein3e-0650.8
NC_017516:917817:921739921739922239501Neisseria meningitidis H44/76 chromosome, complete genomeFe-S protein assembly co-chaperone HscB3e-0650.8
NC_013016:1257942:127587312758731276373501Neisseria meningitidis alpha14 chromosome, complete genomechaperone protein3e-0650.8