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Query: NC_007797:441782:451464 Anaplasma phagocytophilum HZ, complete genome

Start: 451464, End: 452069, Length: 606

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006833:806467:814815814815815348534Wolbachia endosymbiont strain TRS of Brugia malayi, completeNADH:ubiquinone oxidoreductase chain J4e-1581.3
NC_002978:918000:925042925042925629588Wolbachia endosymbiont of Drosophila melanogaster, complete genomeNADH dehydrogenase I, J subunit7e-1580.5
NC_012416:979484:985173985173985760588Wolbachia sp. wRi, complete genomeNADH dehydrogenase I, J subunit1e-1480.1
NC_010981:1053533:106083710608371061424588Wolbachia pipientis, complete genomeNADH dehydrogenase I, J subunit1e-1479.3
NC_008358:1789816:179529917952991795892594Hyphomonas neptunium ATCC 15444, complete genomeNADH-quinone oxidoreductase, J subunit5e-1167.4
NC_019907:287339:301646301646302254609Liberibacter crescens BT-1 chromosome, complete genomeNADH-ubiquinone oxidoreductase subunit J5e-0960.8
NC_007205:841818:857541857541858173633Candidatus Pelagibacter ubique HTCC1062, complete genomeNADH Dehydrogenase I Chain J4e-0858.2
NC_009883:1429000:145053014505301451147618Rickettsia bellii OSU 85-389, complete genomeNADH dehydrogenase subunit J3e-0754.7
NC_018643:482676:499390499390500022633Alpha proteobacterium HIMB5 chromosome, complete genomeNADH-ubiquinone/plastoquinone oxidoreductase chain 69e-0753.5
NC_015581:771482:789793789793790434642Thioalkalimicrobium cyclicum ALM1 chromosome, complete genomeNADH-ubiquinone/plastoquinone oxidoreductase chain 62e-0652.8
NC_017033:1525132:152669515266951527348654Frateuria aurantia DSM 6220 chromosome, complete genomeNADH:ubiquinone oxidoreductase subunit 6 (chain J)3e-0652