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Query: NC_007797:411630:422137 Anaplasma phagocytophilum HZ, complete genome

Start: 422137, End: 423816, Length: 1680

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005295:845000:8499508499508514221473Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein1e-27125
NC_006832:825000:8298258298258313091485Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein1e-27124
NC_006831:821000:8257178257178272011485Ehrlichia ruminantium str. Gardel, complete genomehypothetical protein1e-27124
NC_005295:845000:8519258519258536191695Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein1e-20102
NC_006832:825000:8318008318008334941695Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein1e-20102
NC_006831:821000:8276798276798293731695Ehrlichia ruminantium str. Gardel, complete genomehypothetical protein1e-20101
NC_012416:753500:7905837905837925621980Wolbachia sp. wRi, complete genomePutative outer membrane protein2e-1170.9
NC_016929:55974:7766177661789831323Rickettsia canadensis str. CA410 chromosome, complete genomeDNA topoisomerase IV subunit A7e-0755.8
NC_017044:80384:9649896498978141317Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein1e-0655.5
NC_016913:1066790:1072230107223010735461317Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein1e-0655.1
NC_017062:61500:8268382683840051323Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein1e-0655.1