Pre_GI: BLASTP Hits

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Query: NC_007797:411630:418811 Anaplasma phagocytophilum HZ, complete genome

Start: 418811, End: 420421, Length: 1611

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006831:821000:8276798276798293731695Ehrlichia ruminantium str. Gardel, complete genomehypothetical protein2e-36154
NC_005295:845000:8519258519258536191695Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein5e-36152
NC_006832:825000:8318008318008334941695Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein5e-36152
NC_005295:845000:8499508499508514221473Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein6e-31135
NC_006831:821000:8257178257178272011485Ehrlichia ruminantium str. Gardel, complete genomehypothetical protein6e-31135
NC_006832:825000:8298258298258313091485Ehrlichia ruminantium str. Welgevonden, complete genomehypothetical protein6e-31135
NC_012416:753500:7905837905837925621980Wolbachia sp. wRi, complete genomePutative outer membrane protein3e-1997.1
NC_007797:411630:4170214170214187451725Anaplasma phagocytophilum HZ, complete genomehypothetical protein2e-1894.7
NC_007797:411630:4221374221374238161680Anaplasma phagocytophilum HZ, complete genomehypothetical protein2e-0757.8
NC_017044:80384:9649896498978141317Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein9e-0652.4