Pre_GI: BLASTP Hits

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Query: NC_007797:1016456:1022330 Anaplasma phagocytophilum HZ, complete genome

Start: 1022330, End: 1022932, Length: 603

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012691:1144715:116666711666671167323657Tolumonas auensis DSM 9187, complete genomethiamine-phosphate pyrophosphorylase8e-39159
NC_003295:112778:1258431258431269941152Ralstonia solanacearum GMI1000, complete genomePROBABLE THIAMINE-PHOSPHATE PYROPHOSPHORYLASE PROTEIN1e-28125
NC_011988:924721:929839929839930450612Agrobacterium vitis S4 chromosome 2, complete genomethiamine-phosphate pyrophosphorylase protein1e-28125
NC_013741:687546:692257692257692871615Archaeoglobus profundus DSM 5631, complete genomethiamine-phosphate pyrophosphorylase2e-22105
NC_007503:1111457:112691811269181127565648Carboxydothermus hydrogenoformans Z-2901, complete genomethiamine-phosphate pyrophosphorylase2e-1892
NC_014804:401313:421777421777422406630Thermococcus barophilus MP chromosome, complete genomethiamin-phosphate pyrophosphorylase3e-1891.7
NC_013790:2337000:235244423524442353103660Methanobrevibacter ruminantium M1 chromosome, complete genomethiamine monophosphate synthase ThiE2e-1789.4
NC_012691:241404:245446245446246081636Tolumonas auensis DSM 9187, complete genomethiamine-phosphate pyrophosphorylase3e-1788.2
NC_004193:375416:501449501449502069621Oceanobacillus iheyensis HTE831, complete genomethiamine phosphate synthase chain B1e-1686.7
NC_020911:4428000:444607144460714446679609Octadecabacter antarcticus 307, complete genomethiamine-phosphate pyrophosphorylase6e-1684
NC_015144:1453500:147067314706731471332660Weeksella virosa DSM 16922 chromosome, complete genomethiamine-phosphate pyrophosphorylase6e-1684
NC_016048:2907702:293108029310802931718639Oscillibacter valericigenes Sjm18-20, complete genomethiamine-phosphate pyrophosphorylase8e-1683.6
NC_017243:349144:352639352639353340702Brachyspira intermedia PWS/A chromosome, complete genomethiamine-phosphate pyrophosphorylase4e-1581.3
NC_015425:2144639:214899821489982149612615Clostridium botulinum BKT015925 chromosome, complete genomethiamine-phosphate diphosphorylase7e-1580.5
NC_010175:448020:472705472705473355651Chloroflexus aurantiacus J-10-fl, complete genomethiamine-phosphate pyrophosphorylase1e-1480.1
NC_012032:448161:472847472847473497651Chloroflexus sp. Y-400-fl, complete genomethiamine-phosphate pyrophosphorylase1e-1480.1
NC_013517:1249466:125997812599781260571594Sebaldella termitidis ATCC 33386, complete genomethiamine-phosphate pyrophosphorylase1e-1479.3
NC_008593:1917118:192274919227491923363615Clostridium novyi NT, complete genomethiamine-phosphate pyrophosphorylase3e-1478.6
NC_013665:1123943:112394311239431124590648Methanocella paludicola SANAE, complete genomethiamine-phosphate pyrophosphorylase6e-1477.4
NC_010337:98974:1000791000791014431365Heliobacterium modesticaldum Ice1, complete genomethiamine monophosphate synthase, putative7e-1477
NC_008525:606986:615463615463616113651Pediococcus pentosaceus ATCC 25745, complete genomeThiamine monophosphate synthase7e-1477
NC_012489:4336790:4356351435635143578321482Gemmatimonas aurantiaca T-27, complete genomethiamine-phosphate pyrophosphorylase/phosphomethylpyrimidine kinase2e-1375.5
NC_003454:249304:253356253356253976621Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeThiamin-phosphate pyrophosphorylase2e-1375.5
NC_014828:1632000:163402616340261634691666Ethanoligenens harbinense YUAN-3 chromosome, complete genomethiamine-phosphate pyrophosphorylase3e-1375.1
NC_009513:1065704:106654010665401067187648Lactobacillus reuteri F275, complete genomethiamine-phosphate pyrophosphorylase3e-1374.7
NC_015275:3407358:340673034067303407371642Clostridium lentocellum DSM 5427 chromosome, complete genomeThiamine-phosphate pyrophosphorylase3e-1374.7
NC_015732:191554:194001194001194636636Spirochaeta caldaria DSM 7334 chromosome, complete genomeThiamine-phosphate pyrophosphorylase7e-1373.6
NC_015186:535727:539511539511540131621Acidiphilium multivorum AIU301, complete genomethiamine-phosphate pyrophosphorylase1e-1273.2
NC_014831:2201246:222146822214682222166699Thermaerobacter marianensis DSM 12885 chromosome, complete genomethiamine-phosphate diphosphorylase1e-1272.8
NC_014537:1146000:114604311460431146660618Vulcanisaeta distributa DSM 14429 chromosome, complete genomethiamine-phosphate pyrophosphorylase2e-1272.4
NC_003228:2973266:298350429835042984118615Bacteroides fragilis NCTC 9343, complete genomethiamine-phosphate pyrophosphorylase2e-1272.4
NC_009484:429269:434478434478435098621Acidiphilium cryptum JF-5 chromosome, complete genomethiamine-phosphate pyrophosphorylase2e-1272.4
NC_015318:426707:449028449028449627600Hippea maritima DSM 10411 chromosome, complete genomeThiamine-phosphate pyrophosphorylase2e-1272
NC_006347:2899653:290989029098902910504615Bacteroides fragilis YCH46, complete genomethiamine-phosphate pyrophosphorylase4e-1271.2
NC_014315:2659479:268207226820722682725654Nitrosococcus watsoni C-113 chromosome, complete genomethiamine-phosphate pyrophosphorylase4e-1271.2
NC_006300:600516:629920629920630582663Mannheimia succiniciproducens MBEL55E, complete genomethiamine-phosphate pyrophosphorylase2e-1168.9
NC_014314:238043:238043238043238684642Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completethiamine-phosphate pyrophosphorylase5e-1167.8
NC_009664:1434974:143582214358221436463642Kineococcus radiotolerans SRS30216, complete genomethiamine-phosphate pyrophosphorylase9e-1166.6
NC_014160:719408:738439738439739095657Thermosphaera aggregans DSM 11486 chromosome, complete genomethiamine-phosphate diphosphorylase1e-1066.2
NC_015638:1824794:185697718569771857627651Lacinutrix sp. 5H-3-7-4 chromosome, complete genomeThiamine-phosphate pyrophosphorylase2e-1065.5
NC_014364:773500:789600789600790253654Spirochaeta smaragdinae DSM 11293 chromosome, complete genomethiamine-phosphate pyrophosphorylase3e-1065.1
NC_015499:491423:4971724971724981791008Thermodesulfobium narugense DSM 14796 chromosome, complete genomeThiamine-phosphate pyrophosphorylase8e-1063.5
NC_010376:186510:239791239791240429639Finegoldia magna ATCC 29328, complete genomethiamine-phosphate pyrophosphorylase1e-0963.2
NC_013174:1254874:125564412556441256390747Jonesia denitrificans DSM 20603, complete genomeThiamine-phosphate diphosphorylase4e-0961.2
NC_015425:718384:734322734322734972651Clostridium botulinum BKT015925 chromosome, complete genomethiamine-phosphate pyrophosphorylase1e-0859.7
NC_016616:1091606:109160610916061092553948Dechlorosoma suillum PS chromosome, complete genomethiamine monophosphate synthase2e-0858.9
NC_021171:1689518:170435717043571704959603Bacillus sp. 1NLA3E, complete genometranscriptional regulator TenI4e-0858.2
NC_019896:2805098:283169628316962832313618Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeRegulatory protein TenI7e-0857
NC_005945:754517:755529755529756149621Bacillus anthracis str. Sterne, complete genometranscriptional regulator TenI7e-0753.9
NC_020291:5409587:540958754095875410183597Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomethiamine-phosphate pyrophosphorylase ThiE3e-0652
NC_015942:3185193:318998031899803190633654Acidithiobacillus ferrivorans SS3 chromosome, complete genomeThiamine-phosphate pyrophosphorylase7e-0650.4