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Query: NC_007797:1016456:1019182 Anaplasma phagocytophilum HZ, complete genome

Start: 1019182, End: 1019460, Length: 279

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006833:838330:840454840454840732279Wolbachia endosymbiont strain TRS of Brugia malayi, completeYggT family membrane protein2e-1891.3
NC_012988:4633930:464066746406674640957291Methylobacterium extorquens DM4, complete genomehypothetical protein2e-0651.2
NC_012808:4235567:424230742423074242597291Methylobacterium extorquens AM1, complete genomehypothetical protein2e-0651.2
NC_011757:4293000:429751142975114297801291Methylobacterium chloromethanicum CM4, complete genomeprotein of unknown function YGGT2e-0651.2
NC_010172:4185904:419396141939614194272312Methylobacterium extorquens PA1, complete genomeprotein of unknown function YGGT2e-0650.8