Pre_GI: BLASTP Hits

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Query: NC_007606:3842708:3842708 Shigella dysenteriae Sd197, complete genome

Start: 3842708, End: 3845713, Length: 3006

Host Lineage: Shigella dysenteriae; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. Causes bacillary dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. Shigella dysenteriae is the major cause of Shigella-related deaths in developing nations, mostly in young children.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:5013695:5030350503035050325782229Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein01089
NC_013008:5196080:5212845521284552150732229Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein01089
NC_011353:5240020:5256784525678452590122229Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein01089
NC_002655:5194804:5211569521156952137972229Escherichia coli O157:H7 EDL933, complete genomeputative vimentin01089
NC_002695:5164819:5181584518158451838122229Escherichia coli O157:H7 str. Sakai, complete genomeputative vimentin01089
CU928160:4395156:4410498441049844127262229Escherichia coli IAI1 chromosome, complete genomeconserved hypothetical protein; putative nucleoside triphosphate hydrolase domain01087
NC_011741:4395156:4410498441049844127262229Escherichia coli IAI1 chromosome, complete genomehypothetical protein01087
NC_013364:5040268:5059240505924050614682229Escherichia coli O111:H- str. 11128, complete genomehypothetical protein01087
CP002516:4431235:4431235443123544334632229Escherichia coli KO11, complete genomehypothetical protein01085
NC_000913:4307471:4325158432515843273862229Escherichia coli K12, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01085
AC_000091:4313167:4331813433181343340412229Escherichia coli W3110 DNA, complete genomeconserved hypothetical protein with nucleoside triphosphate hydrolase domain01085
NC_010473:4409492:4425520442552044277482229Escherichia coli str. K-12 substr. DH10B, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01085
NC_012759:4247865:4263893426389342661212229Escherichia coli BW2952 chromosome, complete genomehypothetical protein01085
NC_016902:4431235:4431235443123544334632229Escherichia coli KO11FL chromosome, complete genomehypothetical protein01085
CP002185:4566150:4585076458507645873042229Escherichia coli W, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01085
NC_008253:4541915:4559237455923745614652229Escherichia coli 536, complete genomehypothetical protein YjdA01083
NC_011751:4795928:4812691481269148149192229Escherichia coli UMN026 chromosome, complete genomehypothetical protein01083
NC_010498:4656716:4672087467208746743152229Escherichia coli SMS-3-5, complete genomehypothetical protein01082
AP010958:5022196:5037718503771850399462229Escherichia coli O103:H2 str. 12009 DNA, complete genomeconserved hypothetical protein01082
NC_012947:4106031:4106031410603141082592229Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein01082
NC_012967:4289929:4305849430584943080772229Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein01082
NC_013353:5022196:5037718503771850399462229Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein01082
NC_011748:4695932:4711384471138447136122229Escherichia coli 55989, complete genomehypothetical protein01079
CU928145:4695932:4711384471138447136122229Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein; putative nucleoside triphosphate hydrolase domain01079
NC_009801:4643000:4658535465853546607632229Escherichia coli E24377A, complete genomehypothetical protein01076
NC_009800:4332229:4351156435115643533842229Escherichia coli HS, complete genomehypothetical protein01076
NC_011415:4582388:4597912459791246001402229Escherichia coli SE11 chromosome, complete genomehypothetical protein01076
NC_016822:4686971:4702375470237547046032229Shigella sonnei 53G, complete genomehypothetical protein01075
NC_010468:4305105:4305105430510543073332229Escherichia coli ATCC 8739, complete genome01075
NC_007384:4530000:4545459454545945476872229Shigella sonnei Ss046, complete genomeputative vimentin01072
NC_011750:4719477:4734858473485847370862229Escherichia coli IAI39 chromosome, complete genomehypothetical protein01071
NC_007613:4156841:4176686417668641788452160Shigella boydii Sb227, complete genome01070
NC_011742:4569683:4587706458770645899342229Escherichia coli S88 chromosome, complete genomehypothetical protein01065
NC_008563:4656000:4673178467317846754062229Escherichia coli APEC O1, complete genomeconserved hypothetical protein with nucleoside triphosphate hydrolase domain01065
NC_004431:4867648:4885671488567148878992229Escherichia coli CFT073, complete genomeHypothetical protein yjdA01044
NC_007384:3151344:3160819316081931624041586Shigella sonnei Ss046, complete genome2e-130467
NC_010468:906957:9224059224059239151511Escherichia coli ATCC 8739, complete genome3e-113410
NC_009255:351695:3581563581563606062451Burkholderia vietnamiensis G4 chromosome 2, complete sequencehypothetical protein6e-75283
NC_014366:1663034:1674045167404516764862442Gamma proteobacterium HdN1, complete genomehypothetical protein7e-72273
NC_012912:4167429:4175210417521041775942385Dickeya zeae Ech1591, complete genomehypothetical protein6e-63243
NC_011884:2921618:2932276293227629346422367Cyanothece sp. PCC 7425, complete genomehypothetical protein2e-22108
NC_007606:2353098:2361959236195923643542396Shigella dysenteriae Sd197, complete genome3e-0758.2