Pre_GI: BLASTN Hits

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Query: NC_007530:467993 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 467993, End: 490660, Length: 22668

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009922:86826286826289020421943Alkaliphilus oremlandii OhILAs, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_007530:37496453749645376944819804Bacillus anthracis str. 'Ames Ancestor', complete genome2e-0765.9BLASTN svgBLASTP svg
NC_007530:34626243462624348669024067Bacillus anthracis str. 'Ames Ancestor', complete genome6e-38167BLASTN svgBLASTP svg
NC_003997:46799346799349066022668Bacillus anthracis str. Ames, complete genome025510BLASTN svgBLASTP svg
NC_003997:3724702*3724702376594941248Bacillus anthracis str. Ames, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_003997:34624973462497348209919603Bacillus anthracis str. Ames, complete genome6e-38167BLASTN svgBLASTP svg
NC_005945:467427*46742749070323277Bacillus anthracis str. Sterne, complete genome025510BLASTN svgBLASTP svg
NC_005945:37476523747652376644918798Bacillus anthracis str. Sterne, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_005945:34631993463199348612522927Bacillus anthracis str. Sterne, complete genome6e-38167BLASTN svgBLASTP svg
NC_011772:24959722495972251811522144Bacillus cereus G9842, complete genome2e-19105BLASTN svgBLASTP svg
NC_011772:37493993749399376960320205Bacillus cereus G9842, complete genome4e-42180BLASTN svgBLASTP svg
NC_008598:21978219784828726310Bacillus thuringiensis str. Al Hakam plasmid pALH1, complete6e-35157BLASTN svgBLASTP svg
NC_008600:2353696*2353696237619322498Bacillus thuringiensis str. Al Hakam, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010183:27107271075399926893Bacillus weihenstephanensis KBAB4 plasmid pBWB404, complete6e-32147BLASTN svgBLASTP svg
NC_010184:36318913631891365447522585Bacillus weihenstephanensis KBAB4, complete genome4e-116426BLASTN svgBLASTP svg
NC_010184:34647073464707348723922533Bacillus weihenstephanensis KBAB4, complete genome3e-40174BLASTN svgBLASTP svg