Pre_GI: BLASTP Hits

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Query: NC_007530:5197854:5216241 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 5216241, End: 5216438, Length: 198

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017200:5325977:534431353443135344510198Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein1e-31134
NC_005945:5202176:521748652174865217683198Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-31134
NC_006274:5267585:528973752897375289934198Bacillus cereus E33L, complete genomehypothetical protein1e-31134
NC_003997:5200805:521611552161155216312198Bacillus anthracis str. Ames, complete genomehypothetical protein1e-31134
NC_012659:5200831:521614152161415216338198Bacillus anthracis str. A0248, complete genomehypothetical protein1e-31134
NC_016771:5191937:521028052102805210477198Bacillus cereus NC7401, complete genomehypothetical protein1e-31134
NC_016779:5189139:521172852117285211925198Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-31134
NC_004722:5381208:540049654004965400672177Bacillus cereus ATCC 14579, complete genomehypothetical Cytosolic Protein4e-27119
NC_009328:3504454:353817835381783538375198Geobacillus thermodenitrificans NG80-2 chromosome, complete genomehypothetical protein6e-24109
NC_015690:8645500:865009786500978650330234Paenibacillus mucilaginosus KNP414 chromosome, complete genomeYyzM1e-1892
NC_016935:8716704:872532687253268725559234Paenibacillus mucilaginosus 3016 chromosome, complete genomeYyzM protein1e-1892
NC_007168:2631535:263497026349702635173204Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein1e-1788.6
NC_013406:7092510:709993970999397100160222Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein2e-1684.3
NC_018664:3009166:300896630089663009169204Clostridium acidurici 9a chromosome, complete genomehypothetical protein DUF9517e-1682.4
NC_009495:3832500:387237838723783872575198Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein7e-1682.4
NC_010516:3903867:394373639437363943933198Clostridium botulinum B1 str. Okra, complete genomehypothetical protein7e-1682.4
NC_009699:3940984:398085339808533981050198Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-1580.5
NC_015519:2739347:274138027413802741586207Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein7e-1475.9
NC_009706:3882500:394987639498763950085210Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein1e-1375.5
NC_011837:3814000:388137938813793881588210Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-1375.5
NC_013740:15401:226702267022870201Acidaminococcus fermentans DSM 20731, complete genomeprotein of unknown function DUF9511e-1375.1
NC_009012:2953638:298176929817692981969201Clostridium thermocellum ATCC 27405, complete genomeprotein of unknown function DUF9513e-1373.9
NC_004668:3156247:317984731798473180032186Enterococcus faecalis V583, complete genomehypothetical protein1e-1272
NC_014964:2301835:232586023258602326066207Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein2e-1271.2
NC_010321:2319820:234384523438452344051207Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completehypothetical protein2e-1271.2
NC_015520:224136:235846235846236055210Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein3e-1270.5
NC_015275:1223088:123497912349791235152174Clostridium lentocellum DSM 5427 chromosome, complete genomeprotein of unknown function DUF9513e-1270.5
NC_006177:3549467:354925535492553549479225Symbiobacterium thermophilum IAM 14863, complete genomehypothetical protein4e-1270.1
NC_014251:243700:248589248589248837249Streptococcus pneumoniae TCH8431/19A chromosome, complete genomehypothetical protein2e-1064.3
NC_013171:228356:235214235214235441228Anaerococcus prevotii DSM 20548, complete genomeprotein of unknown function DUF9512e-1064.3
NC_012781:3087467:310366631036663103854189Eubacterium rectale ATCC 33656, complete genomehypothetical protein5e-1063.2
NC_014498:1:291829183112195Streptococcus pneumoniae 670-6B chromosome, complete genomehypothetical protein1e-0962
NC_012469:1:291829183112195Streptococcus pneumoniae Taiwan19F-14, complete genomehypothetical protein1e-0962
NC_012778:2015409:202083620208362021033198Eubacterium eligens ATCC 27750, complete genomehypothetical protein1e-0962
NC_014314:1:426042604505246Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completehypothetical protein3e-0753.9
NC_010163:63209:727757277572945171Acholeplasma laidlawii PG-8A chromosome, complete genomehypothetical protein2e-0651.6
NC_015499:197945:211471211471211656186Thermodesulfobium narugense DSM 14796 chromosome, complete genomeprotein of unknown function DUF9512e-0651.2