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Query: NC_007530:5006319:5021336 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 5021336, End: 5022046, Length: 711

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006274:5085860:509059250905925091302711Bacillus cereus E33L, complete genomehypothetical protein7e-127452
NC_003997:5006193:502121050212105021920711Bacillus anthracis str. Ames, complete genomehypothetical protein7e-127452
NC_005945:5011857:502254550225455023255711Bacillus anthracis str. Sterne, complete genomehypothetical protein7e-127452
NC_012659:5006219:502123650212365021940705Bacillus anthracis str. A0248, complete genomehypothetical protein8e-127452
NC_012581:5008749:502376650237665024470705Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein3e-126451
NC_014335:4969549:497428149742814974991711Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-126451
NC_011969:4993386:499879349987934999503711Bacillus cereus Q1 chromosome, complete genomehypothetical protein2e-125447
NC_011658:5049349:505475550547555055459705Bacillus cereus AH187 chromosome, complete genomehypothetical protein3e-125447
NC_008600:5046000:504989650498965050606711Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein3e-125447
NC_016779:5009320:501420350142035014907705Bacillus cereus F837/76 chromosome, complete genomehypothetical protein4e-125447
NC_012472:5055184:506006750600675060771705Bacillus cereus 03BB102, complete genomehypothetical protein4e-125447
NC_003909:4996783:499950849995085000218711Bacillus cereus ATCC 10987, complete genomehypothetical protein2e-124444
NC_017208:5273500:527499752749975275701705Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein3e-123441
NC_011725:5201995:520740252074025208106705Bacillus cereus B4264 chromosome, complete genomehypothetical protein3e-123441
NC_004722:5194000:519945451994545200158705Bacillus cereus ATCC 14579, complete genomehypothetical protein3e-123441
NC_014171:5107956:511163251116325112336705Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein5e-123439
NC_011772:5158680:516125351612535161957705Bacillus cereus G9842, complete genomehypothetical protein9e-123439
NC_010184:5051287:505405850540585054768711Bacillus weihenstephanensis KBAB4, complete genomeProtein of unknown function DUF17792e-119428
NC_009674:3863667:386843738684373869144708Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein4e-111400
NC_021171:4588792:461585346158534616605753Bacillus sp. 1NLA3E, complete genomehypothetical protein9e-1994
NC_014829:4346500:437027743702774371053777Bacillus cellulosilyticus DSM 2522 chromosome, complete genomeprotein of unknown function DUF17793e-0962.4
NC_019970:2551607:255701725570172557769753Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeProtein of unknown function (DUF1779)3e-0755.5
NC_015555:2259500:228513022851302286011882Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeprotein of unknown function DUF17794e-0755.1