Pre_GI: BLASTP Hits

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Query: NC_007530:4474000:4478800 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 4478800, End: 4479915, Length: 1116

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4474000:4478700447870044798151116Bacillus anthracis str. A0248, complete genomeputative aminopeptidase0773
NC_011772:4606000:4606146460614646072611116Bacillus cereus G9842, complete genomeputative aminopeptidase0764
NC_004722:4614442:4616608461660846177231116Bacillus cereus ATCC 14579, complete genomeAminopeptidase0768
NC_011725:4636521:4641419464141946425341116Bacillus cereus B4264 chromosome, complete genomeaminopeptidase0768
NC_005957:4472800:4472800447280044739151116Bacillus thuringiensis serovar konkukian str. 97-27, completeaminopeptidase0771
NC_011773:4541306:4541306454130645424211116Bacillus cereus AH820 chromosome, complete genomeputative aminopeptidase0771
NC_011969:4396000:4401179440117944022941116Bacillus cereus Q1 chromosome, complete genomeaminopeptidase0771
NC_017200:4484399:4488569448856944896841116Bacillus thuringiensis serovar finitimus YBT-020 chromosome,aminopeptidase0771
NC_005945:4473790:4479362447936244804771116Bacillus anthracis str. Sterne, complete genomeaminopeptidase, putative0773
NC_003997:4473973:4478673447867344797881116Bacillus anthracis str. Ames, complete genomeaminopeptidase, putative0773
NC_012581:4478036:4480196448019644813111116Bacillus anthracis str. CDC 684 chromosome, complete genomeputative aminopeptidase0773
NC_010184:4497473:4501466450146645025811116Bacillus weihenstephanensis KBAB4, complete genomepeptidase M29 aminopeptidase II0762
NC_018870:484000:4853984853984866091212Thermacetogenium phaeum DSM 12270 chromosome, complete genomepeptidase M29 aminopeptidase II2e-151535
NC_021184:3571014:3593247359324735943621116Desulfotomaculum gibsoniae DSM 7213, complete genomeleucyl aminopeptidase (aminopeptidase T)4e-149527
NC_016641:5306000:5325575532557553266901116Paenibacillus terrae HPL-003 chromosome, complete genomeleucyl aminopeptidase9e-146516
NC_014721:1629063:1634738163473816358531116Caldicellulosiruptor kristjanssonii 177R1B chromosome, completepeptidase m29 aminopeptidase ii3e-135481
NC_009483:2201986:2213158221315822142641107Geobacter uraniireducens Rf4 chromosome, complete genomepeptidase M29, aminopeptidase II1e-85317
NC_008609:2254392:2274227227422722753301104Pelobacter propionicus DSM 2379, complete genomepeptidase M29, aminopeptidase II1e-84313
NC_007517:1792000:1796377179637717974831107Geobacter metallireducens GS-15, complete genomePeptidase M29, aminopeptidase II3e-81301
NC_009828:1474970:1485698148569814867651068Thermotoga lettingae TMO, complete genomepeptidase M29 aminopeptidase II2e-61236
NC_014314:238043:2721582721582732641107Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completepeptidase M29 aminopeptidase II5e-60231
NC_014831:285759:2900782900782911841107Thermaerobacter marianensis DSM 12885 chromosome, complete genomepeptidase M29 aminopeptidase II3e-57222
NC_020387:745353:7593977593977605061110Dehalococcoides mccartyi BTF08, complete genomeaminopeptidase7e-53207
NC_014654:1548194:1551693155169315527961104Halanaerobium sp. 'sapolanicus' chromosome, complete genomepeptidase M29 aminopeptidase II5e-51201
NC_013202:771161:7994067994068005031098Halomicrobium mukohataei DSM 12286, complete genomepeptidase M29 aminopeptidase II3e-44179
NC_019962:3331849:3333791333379133348881098Natrinema pellirubrum DSM 15624, complete genomeleucyl aminopeptidase (aminopeptidase T)1e-40167
NC_013967:1687825:1688224168822416893181095Haloferax volcanii DS2 chromosome, complete genomeaminopeptidase homolog6e-40165
NC_008699:3516608:3519450351945035205651116Nocardioides sp. JS614, complete genomeLeucyl aminopeptidase (aminopeptidase T)-like7e-35148
NC_015760:61345:7902779027802681242Streptococcus salivarius CCHSS3, complete genomeaminopeptidase pepS7e-21101
NC_006449:58436:7613276132773731242Streptococcus thermophilus CNRZ1066, complete genomeaminopeptidase PepS1e-20100
NC_006448:59654:7734977349785901242Streptococcus thermophilus LMG 18311, complete genomeaminopeptidase PepS1e-20100
NC_012985:465354:4671984671984684541257Candidatus Liberibacter asiaticus str. psy62, complete genomeaminopeptidase protein6e-1995.1
NC_014171:343834:3596423596423608711230Bacillus thuringiensis BMB171 chromosome, complete genomeaminopeptidase1e-1894.4
NC_011725:334000:3509483509483521771230Bacillus cereus B4264 chromosome, complete genomeaminopeptidase1e-1894.4
NC_011772:323050:3371583371583383871230Bacillus cereus G9842, complete genomeaminopeptidase AmpS1e-1894.4
NC_009937:5033152:5039104503910450403601257Azorhizobium caulinodans ORS 571, complete genomeaminopeptidase II3e-1892.8
NC_012526:131000:1324781324781337341257Deinococcus deserti VCD115, complete genomeputative Aminopeptidase, (Heat stable aminopeptidase)6e-1892
NC_014774:239865:2560272560272572831257Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completeaminopeptidase protein3e-1582.8
NC_014624:2668157:2687320268732026885491230Eubacterium limosum KIST612 chromosome, complete genomepeptidase M29 aminopeptidase II9e-1478.2
NC_012793:2122036:2124397212439721256381242Geobacillus sp. WCH70, complete genomepeptidase M29 aminopeptidase II1e-1377.8
NC_010376:28812:4448744487457191233Finegoldia magna ATCC 29328, complete genomeaminopeptidase II1e-1274.7
NC_015161:2018493:2039945203994520412011257Deinococcus proteolyticus MRP chromosome, complete genomepeptidase M29 aminopeptidase II9e-1271.6
NC_007795:1922000:1968999196899919702551257Staphylococcus aureus subsp. aureus NCTC 8325, complete genomeaminopeptidase PepS, putative3e-1169.7
NC_013894:1288282:1288959128895912900351077Thermocrinis albus DSM 14484 chromosome, complete genomehypothetical protein4e-1065.9
NC_008262:2169262:2171017217101721722521236Clostridium perfringens SM101, complete genomeaminopeptidase8e-0961.6
NC_003366:2286083:2287837228783722890721236Clostridium perfringens str. 13, complete genomeaminopeptidase II9e-0961.6
NC_008261:2481500:2501693250169325029281236Clostridium perfringens ATCC 13124, complete genomeaminopeptidase9e-0961.6
NC_015954:2873402:287788428778842878849966Halophilic archaeon DL31 chromosome, complete genomeleucyl aminopeptidase2e-0653.9