Pre_GI: BLASTP Hits

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Query: NC_007530:4400152:4409215 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 4409215, End: 4410189, Length: 975

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016771:4333000:434065543406554341629975Bacillus cereus NC7401, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha3e-174611
NC_005945:4399756:440977744097774410751975Bacillus anthracis str. Sterne, complete genomeacetyl-CoA carboxylase alpha subunit3e-174611
NC_003997:4399067:440908844090884410062975Bacillus anthracis str. Ames, complete genomeacetyl-CoA carboxylase alpha subunit3e-174611
NC_014335:4327584:433759543375954338569975Bacillus cereus biovar anthracis str. CI chromosome, completeacetyl-CoA carboxylase subunit alpha3e-174611
NC_012472:4400420:440664644066464407620975Bacillus cereus 03BB102, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit3e-174611
NC_006274:4448293:445749544574954458469975Bacillus cereus E33L, complete genomeacetyl-CoA carboxylase alpha subunit3e-174611
NC_011658:4379274:438687243868724387846975Bacillus cereus AH187 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha3e-174611
NC_011773:4461758:447082144708214471795975Bacillus cereus AH820 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha3e-174611
NC_012659:4399094:440911544091154410089975Bacillus anthracis str. A0248, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha3e-174611
NC_016779:4361140:437130543713054372279975Bacillus cereus F837/76 chromosome, complete genomeAcetyl-coenzyme A carboxyl transferase alpha chain1e-173608
NC_017200:4401945:441304944130494414023975Bacillus thuringiensis serovar finitimus YBT-020 chromosome,acetyl-CoA carboxylase carboxyltransferase subunit alpha1e-172605
NC_010184:4425676:443463344346334435607975Bacillus weihenstephanensis KBAB4, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit1e-169595
NC_009674:3344000:335458433545843355558975Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha1e-166585
NC_011725:4562709:456896645689664569940975Bacillus cereus B4264 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha4e-166583
NC_014171:4447856:445790444579044458878975Bacillus thuringiensis BMB171 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha2e-165582
NC_019978:393351:406300406300407289990Halobacteroides halobius DSM 5150, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit2e-89329
NC_015425:34861:502185021851162945Clostridium botulinum BKT015925 chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha2e-88326
NC_012880:3421500:345319234531923454151960Dickeya dadantii Ech703, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit3e-87322
NC_007907:1547539:155288615528861553845960Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-86318
NC_004757:1089057:110861011086101109578969Nitrosomonas europaea ATCC 19718, complete genomeCarboxyl transferase, alpha subunit8e-86317
NC_010084:1299387:132143813214381322409972Burkholderia multivorans ATCC 17616 chromosome 1, completeacetyl-CoA carboxylase carboxyltransferase subunit alpha2e-85316
NC_016513:1400899:140468114046811405667987Aggregatibacter actinomycetemcomitans ANH9381 chromosome, completeacetyl-CoA carboxylase carboxyltransferase subunit alpha3e-85315
NC_013416:1091432:109649910964991097452954Aggregatibacter actinomycetemcomitans D11S-1, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit2e-85315
NC_007347:1215358:121624412162441217215972Ralstonia eutropha JMP134 chromosome 1, complete sequenceacetyl-CoA carboxylase alpha subunit3e-84311
NC_015138:3160764:317759431775943178568975Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completeacetyl-coenzyme A carboxylase carboxyl transferase subunit alpha2e-83308
NC_018419:1397914:141578514157851416744960Secondary endosymbiont of Ctenarytaina eucalypti chromosome,acetyl-CoA carboxylase, carboxyl transferase, alpha subunit2e-82305
NC_014153:436082:454489454489455466978Thiomonas intermedia K12 chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit3e-81301
NC_015687:3766000:377065437706543771478825Clostridium acetobutylicum DSM 1731 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha6e-81300
NC_003030:3763054:376907137690713769895825Clostridium acetobutylicum ATCC 824, complete genomeAcetyl-CoA carboxylase alpha subunit6e-81300
NC_017295:3762622:376842337684233769247825Clostridium acetobutylicum EA 2018 chromosome, complete genomeAcetyl-CoA carboxylase alpha subunit6e-81300
NC_015499:1403447:140248014024801403457978Thermodesulfobium narugense DSM 14796 chromosome, complete genomeAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha3e-80298
NC_021182:4882494:488639448863944887212819Clostridium pasteurianum BC1, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit4e-79295
NC_014221:1167261:116726111672611168211951Truepera radiovictrix DSM 17093 chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit2e-78292
NC_010674:1170264:118359511835951184419825Clostridium botulinum B str. Eklund 17B, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit4e-78291
NC_010723:1133163:114749211474921148316825Clostridium botulinum E3 str. Alaska E43, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit6e-78291
NC_014109:326500:342600342600343562963Candidatus Riesia pediculicola USDA chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit1e-77290
NC_014328:4546390:455097345509734551818846Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeacetyl-coenzyme A carboxylase subunit alpha2e-76286
NC_013517:1823926:182479018247901825734945Sebaldella termitidis ATCC 33386, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit4e-76285
NC_008593:37456:509165091651761846Clostridium novyi NT, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit8e-76284
NC_016937:1525914:155099015509901551937948Francisella tularensis subsp. tularensis TI0902 chromosome,Acetyl-coenzyme A carboxyl transferase alpha chain2e-74279
NC_008245:1525877:155095315509531551900948Francisella tularensis subsp. tularensis FSC 198, complete genomeAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha2e-74279
NC_020291:1266885:129831312983131299131819Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeacetyl-coenzyme A carboxylase carboxyl transferase subunit alpha4e-74278
NC_004557:81362:9386193861955881728Clostridium tetani E88, complete genomeacetyl-coA carboxylase carboxyl transferase subunit beta/alpha4e-74278
NC_015638:23654:470254702547978954Lacinutrix sp. 5H-3-7-4 chromosome, complete genomeacetyl-coenzyme A carboxylase carboxyl transferase subunit alpha2e-73276
NC_012658:3923546:392904839290483929887840Clostridium botulinum Ba4 str. 657 chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha3e-73275
NC_009495:3832500:383799538379953838834840Clostridium botulinum A str. ATCC 3502 chromosome, complete genomeacetyl-CoA carboxylase carboxyl transferase subunit alpha6e-73274
NC_009697:3809044:381452938145293815368840Clostridium botulinum A str. ATCC 19397 chromosome, completeacetyl-CoA carboxylase, carboxyl transferase subunit alpha6e-73274
NC_009698:3706154:371163937116393712478840Clostridium botulinum A str. Hall chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha6e-73274
NC_010520:3938490:394398939439893944828840Clostridium botulinum A3 str. Loch Maree, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit2e-72272
NC_017297:3939328:394481739448173945656840Clostridium botulinum F str. 230613 chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha2e-72272
NC_009699:3940984:394647339464733947312840Clostridium botulinum F str. Langeland chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha2e-72272
NC_012563:4101000:410651341065134107352840Clostridium botulinum A2 str. Kyoto, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit3e-72272
NC_014472:294775:317315317315318268954Flavobacteriales bacterium HTCC2170 chromosome, complete genomeAcetyl-CoA carboxylase, alpha subunit5e-72271
NC_009617:1278000:128951612895161290334819Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha5e-72271
NC_010516:3903867:390935339093533910192840Clostridium botulinum B1 str. Okra, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit4e-72271
NC_014958:843456:849008849008849949942Deinococcus maricopensis DSM 21211 chromosome, complete genomeacetyl-coenzyme A carboxylase carboxyl transferase subunit alpha2e-71269
NC_010001:649000:663483663483664382900Clostridium phytofermentans ISDg, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit3e-71268
NC_015977:3011177:3036862303686230385711710Roseburia hominis A2-183 chromosome, complete genomeacetyl-coA carboxylase carboxyl transferase subunit beta/alpha6e-71267
NC_016012:805680:811173811173811979807Candidatus Arthromitus sp. SFB-rat-Yit, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha7e-71267
NC_005956:1888500:188940218894021890358957Bartonella henselae str. Houston-1, complete genomeacetyl-CoA carboxylase alpha subunit8e-69260
NC_005955:1540838:154162015416201542576957Bartonella quintana str. Toulouse, complete genomeacetyl-CoA carboxylase alpha subunit5e-68258
NC_014802:392852:415625415625416563939Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, completeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit5e-68258
NC_014225:1403007:1426928142692814279921065Waddlia chondrophila WSU 86-1044 chromosome, complete genomeacetyl-CoA carboxylase carboxyl transferase subunit alpha9e-68257
NC_003912:426676:449446449446450384939Campylobacter jejuni RM1221, complete genomeacetyl-CoA carboxylase alpha subunit8e-68257
NC_015380:99919:1235641235641246491086Candidatus Pelagibacter sp. IMCC9063 chromosome, complete genomeacetyl-coenzyme A carboxyl transferase alpha chain1e-67256
NC_016938:1492486:149484514948451495633789Melissococcus plutonius DAT561 chromosome 1, complete genomeacetyl-coenzyme A carboxyl transferase alpha subunit2e-67256
NC_012846:2299282:230007223000722301028957Bartonella grahamii as4aup, complete genomeacetyl-CoA carboxylase, carboxyl transferase subunit alpha5e-67254
NC_013204:2305140:2326888232688823293352448Eggerthella lenta DSM 2243, complete genomeacetyl-CoA carboxylase, carboxyl transferase, beta subunit6e-67254
NC_008783:29972:457724577246728957Bartonella bacilliformis KC583, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit7e-66251
NC_014393:4988127:499282749928274993609783Clostridium cellulovorans 743B chromosome, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit1e-65249
NC_015275:3299923:330423533042353305173939Clostridium lentocellum DSM 5427 chromosome, complete genomeAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha2e-63243
NC_007205:499808:4987074987074998131107Candidatus Pelagibacter ubique HTCC1062, complete genomeacetyl-CoA carboxylase2e-63242
NC_015391:1323171:133000213300021330793792Carnobacterium sp. 17-4 chromosome, complete genomeacetyl-coenzyme A carboxylase carboxyl transferase subunit alpha4e-63241
NC_008599:1325155:134601313460131346945933Campylobacter fetus subsp. fetus 82-40, complete genomeacetyl-CoA carboxylase, carboxyl transferase, alpha subunit4e-63241
NC_013928:395028:424271424271425041771Streptococcus mutans NN2025, complete genomeacetyl-CoA carboxylase subunit alpha3e-62238
NC_017187:1923733:193928419392841940219936Arcobacter butzleri ED-1, complete genomeacetyl-CoA carboxylase carboxyltransferase subunit alpha2e-60233
NC_012778:1778654:179177617917761792567792Eubacterium eligens ATCC 27750, complete genomeacetyl-CoA carboxylase carboxyl transferase subunit alpha2e-58226
NC_015602:1949610:195737119573711958141771Lactobacillus kefiranofaciens ZW3 chromosome, complete genomeacetyl-CoA carboxylase alpha subunit8e-51201
NC_018528:1932000:194446319444631945233771Lactobacillus helveticus R0052 chromosome, complete genomeacetyl-CoA carboxylase alpha subunit1e-50200
NC_010080:1885677:189575518957551896525771Lactobacillus helveticus DPC 4571, complete genomeAcetyl-CoA carboxylase alpha subunit6e-50197
NC_007512:1459685:1457904145790414596881785Pelodictyon luteolum DSM 273, complete genomeAcetyl-CoA carboxylase alpha subunit-like1e-24114
NC_021177:2241647:2241647224164722430141368Streptomyces fulvissimus DSM 40593, complete genomeAcetyl-CoA carboxylase3e-1375.9
NC_014365:2359760:2377451237745123793431893Desulfarculus baarsii DSM 2075 chromosome, complete genomecarboxyl transferase6e-1375.1