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Query: NC_007530:3581202:3593799 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 3593799, End: 3594710, Length: 912

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011899:948790:949576949576950352777Halothermothrix orenii H 168, complete genomeHelix-turn-helix1e-1584
NC_008600:3611038:362049636204963621416921Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein1e-141502
NC_005945:3581776:359437335943733595284912Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-141502
NC_006274:3661194:367422436742243675135912Bacillus cereus E33L, complete genomehypothetical protein2e-139495
NC_011772:3705878:372210837221083723022915Bacillus cereus G9842, complete genomehypothetical protein3e-127454
NC_007907:2249607:227169822716982272501804Desulfitobacterium hafniense Y51, complete genomehypothetical protein2e-1170.1
NC_003997:3579972:359367235936723594583912Bacillus anthracis str. Ames, complete genomehypothetical protein1e-141502
NC_011773:3615998:362859436285943629505912Bacillus cereus AH820 chromosome, complete genomehypothetical protein8e-141499
NC_011725:3785769:379847237984723799383912Bacillus cereus B4264 chromosome, complete genomehypothetical protein4e-132470
NC_015391:695350:697480697480698343864Carnobacterium sp. 17-4 chromosome, complete genomehypothetical protein3e-28125
NC_015520:1619000:163535816353581636185828Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein3e-1582.8
NC_014330:1957725:1960617196061719619751359Brachyspira pilosicoli 95/1000 chromosome, complete genomehypothetical protein4e-0858.9
NC_012581:639329:643978643978644889912Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein1e-141502
NC_014335:3531931:354452135445213545432912Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein5e-141500
NC_014171:3661512:367773536777353678646912Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein4e-132470
NC_016771:3520522:353422335342233535158936Bacillus cereus NC7401, complete genomehypothetical protein1e-120432
NC_019908:1296870:1306943130694313083011359Brachyspira pilosicoli P43/6/78 chromosome, complete genomehypothetical protein4e-0858.9
NC_008312:2941500:296096029609602961700741Trichodesmium erythraeum IMS101, complete genomehypothetical protein1e-0653.9
NC_012659:3579999:359369935936993594610912Bacillus anthracis str. A0248, complete genomehypothetical protein1e-141502
NC_012472:3625800:363850336385033639414912Bacillus cereus 03BB102, complete genomehypothetical protein1e-141502
NC_005957:3602744:361534136153413616252912Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein2e-139495
NC_017200:3622838:363543236354323636343912Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein3e-123441
NC_017243:685783:6891856891856905671383Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein6e-0962
NC_011296:1039749:104033510403351041108774Thermodesulfovibrio yellowstonii DSM 11347, complete genomehypothetical protein3e-0756.2
NC_016913:83988:105828105828106181354Rickettsia rickettsii str. Brazil chromosome, complete genometranscriptional regulator2e-0756.6
NC_015516:131564:134435134435135322888Melissococcus plutonius ATCC 35311, complete genometranscriptional regulator in cluster with unspecified monosaccharide ABC transport system1e-1894
NC_016938:136331:136331136331137203873Melissococcus plutonius DAT561 chromosome 1, complete genometranscriptional regulator in cluster with unspecified monosaccharide ABC transport system1e-1584