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Query: NC_007530:1007140:1019013 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 1019013, End: 1019177, Length: 165

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005957:1037205:104760710476071047816210Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein8e-1579
NC_006274:1040836:105171610517161051925210Bacillus cereus E33L, complete genomegroup-specific protein8e-1579
NC_005945:1008000:101890610189061019115210Bacillus anthracis str. Sterne, complete genomehypothetical protein8e-1579
NC_004722:1008500:102081110208111020975165Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-1478.6
NC_003997:1007139:101901310190131019177165Bacillus anthracis str. Ames, complete genomehypothetical protein1e-1478.6
NC_011773:1050000:106121810612181061382165Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-1478.6
NC_012659:1008028:101891310189131019077165Bacillus anthracis str. A0248, complete genomehypothetical protein1e-1478.6
NC_014171:1018338:103056210305621030726165Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-1478.6
NC_016779:991298:100007510000751000239165Bacillus cereus F837/76 chromosome, complete genomehypothetical protein1e-1478.6
NC_017208:1050414:106359710635971063761165Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein1e-1478.6
NC_011772:1011220:102109110210911021255165Bacillus cereus G9842, complete genomehypothetical protein4e-1476.6
NC_017200:1157835:117204811720481172212165Bacillus thuringiensis serovar finitimus YBT-020 chromosome,group-specific protein5e-1476.3
NC_011725:1032500:104487010448701045025156Bacillus cereus B4264 chromosome, complete genomehypothetical protein4e-1373.6