Pre_GI: BLASTP Hits

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Query: NC_007384:4530000:4545459 Shigella sonnei Ss046, complete genome

Start: 4545459, End: 4547687, Length: 2229

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007613:4156841:4176686417668641788452160Shigella boydii Sb227, complete genome01319
NC_007606:3842708:3842708384270838457133006Shigella dysenteriae Sd197, complete genome01037
NC_010468:4305105:4305105430510543073332229Escherichia coli ATCC 8739, complete genome01338
AP010958:5022196:5037718503771850399462229Escherichia coli O103:H2 str. 12009 DNA, complete genomeconserved hypothetical protein01347
AC_000091:4313167:4331813433181343340412229Escherichia coli W3110 DNA, complete genomeconserved hypothetical protein with nucleoside triphosphate hydrolase domain01344
NC_008563:4656000:4673178467317846754062229Escherichia coli APEC O1, complete genomeconserved hypothetical protein with nucleoside triphosphate hydrolase domain01319
CU928160:4395156:4410498441049844127262229Escherichia coli IAI1 chromosome, complete genomeconserved hypothetical protein; putative nucleoside triphosphate hydrolase domain01338
CU928145:4695932:4711384471138447136122229Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein; putative nucleoside triphosphate hydrolase domain01353
NC_010473:4409492:4425520442552044277482229Escherichia coli str. K-12 substr. DH10B, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01344
CP002185:4566150:4585076458507645873042229Escherichia coli W, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01343
NC_000913:4307471:4325158432515843273862229Escherichia coli K12, complete genomeconserved protein with nucleoside triphosphate hydrolase domain01344
NC_014219:2253023:2271013227101322746123600Bacillus selenitireducens MLS10 chromosome, complete genomeDynamin family protein5e-0757
NC_010498:4656716:4672087467208746743152229Escherichia coli SMS-3-5, complete genomehypothetical protein01353
NC_013008:5196080:5212845521284552150732229Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein01343
NC_011742:4569683:4587706458770645899342229Escherichia coli S88 chromosome, complete genomehypothetical protein01319
NC_009255:351695:3581563581563606062451Burkholderia vietnamiensis G4 chromosome 2, complete sequencehypothetical protein3e-115416
NC_009801:4643000:4658535465853546607632229Escherichia coli E24377A, complete genomehypothetical protein01349
NC_012947:4106031:4106031410603141082592229Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein01347
NC_013941:5013695:5030350503035050325782229Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein01343
NC_011741:4395156:4410498441049844127262229Escherichia coli IAI1 chromosome, complete genomehypothetical protein01338
NC_011884:2921618:2932276293227629346422367Cyanothece sp. PCC 7425, complete genomehypothetical protein1e-37158
NC_011748:4695932:4711384471138447136122229Escherichia coli 55989, complete genomehypothetical protein01353
NC_009800:4332229:4351156435115643533842229Escherichia coli HS, complete genomehypothetical protein01349
NC_012967:4289929:4305849430584943080772229Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein01347
NC_012759:4247865:4263893426389342661212229Escherichia coli BW2952 chromosome, complete genomehypothetical protein01344
CP002516:4431235:4431235443123544334632229Escherichia coli KO11, complete genomehypothetical protein01344
NC_013364:5040268:5059240505924050614682229Escherichia coli O111:H- str. 11128, complete genomehypothetical protein01339
NC_011750:4719477:4734858473485847370862229Escherichia coli IAI39 chromosome, complete genomehypothetical protein01336
NC_012912:4167429:4175210417521041775942385Dickeya zeae Ech1591, complete genomehypothetical protein3e-92340
NC_016822:4686971:4702375470237547046032229Shigella sonnei 53G, complete genomehypothetical protein01362
NC_011415:4582388:4597912459791246001402229Escherichia coli SE11 chromosome, complete genomehypothetical protein01349
NC_013353:5022196:5037718503771850399462229Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein01347
NC_016902:4431235:4431235443123544334632229Escherichia coli KO11FL chromosome, complete genomehypothetical protein01344
NC_011353:5240020:5256784525678452590122229Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein01343
NC_011751:4795928:4812691481269148149192229Escherichia coli UMN026 chromosome, complete genomehypothetical protein01339
NC_014366:1663034:1674045167404516764862442Gamma proteobacterium HdN1, complete genomehypothetical protein1e-105384
NC_008253:4541915:4559237455923745614652229Escherichia coli 536, complete genomehypothetical protein YjdA01349
NC_004431:4867648:4885671488567148878992229Escherichia coli CFT073, complete genomeHypothetical protein yjdA01308
NC_002695:5164819:5181584518158451838122229Escherichia coli O157:H7 str. Sakai, complete genomeputative vimentin01343
NC_002655:5194804:5211569521156952137972229Escherichia coli O157:H7 EDL933, complete genomeputative vimentin01343