Pre_GI: BLASTP Hits

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Query: NC_007384:4530000:4534325 Shigella sonnei Ss046, complete genome

Start: 4534325, End: 4534882, Length: 558

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016902:4431235:444451644445164445073558Escherichia coli KO11FL chromosome, complete genomephosphonate metabolism protein/1,5-bisphosphokinase PhnN4e-105380
NC_010468:4305105:431787943178794318436558Escherichia coli ATCC 8739, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN4e-105380
CP002516:4431235:444451644445164445073558Escherichia coli KO11, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN4e-105380
NC_000913:4307471:431354843135484314105558Escherichia coli K12, complete genomeribose 1,5-bisphosphokinase4e-105380
AC_000091:4313167:432020343202034320760558Escherichia coli W3110 DNA, complete genomeribose 1,5-bisphosphokinase4e-105380
NC_010473:4409492:441391044139104414467558Escherichia coli str. K-12 substr. DH10B, complete genomeribose 1,5-bisphosphokinase4e-105380
NC_012759:4247865:425228342522834252840558Escherichia coli BW2952 chromosome, complete genomeribose 1,5-bisphosphokinase4e-105380
NC_012947:4106031:411920441192044119761558Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeribose 1,5-bisphosphokinase4e-105380
NC_012967:4289929:429434742943474294904558Escherichia coli B str. REL606 chromosome, complete genomeribose 1,5-bisphosphokinase4e-105380
NC_016822:4686971:469125246912524691809558Shigella sonnei 53G, complete genomeribose 1,5-bisphosphokinase4e-105380
NC_002695:5164819:517038051703805170937558Escherichia coli O157:H7 str. Sakai, complete genomeATP-binding component of phosphonate transport5e-105379
AP010958:5022196:502661450266145027171558Escherichia coli O103:H2 str. 12009 DNA, complete genomeribose 1,5-bisphosphokinase PhnN5e-105379
NC_011353:5240020:524558052455805246137558Escherichia coli O157:H7 str. EC4115 chromosome, complete genomeribose 1,5-bisphosphokinase5e-105379
NC_013008:5196080:520164152016415202198558Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeribose 1,5-bisphosphokinase5e-105379
NC_013353:5022196:502661450266145027171558Escherichia coli O103:H2 str. 12009, complete genomeribose 1,5-bisphosphokinase PhnN5e-105379
NC_013941:5013695:501924650192465019803558Escherichia coli O55:H7 str. CB9615 chromosome, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN5e-105379
NC_002655:5194804:520036552003655200922558Escherichia coli O157:H7 EDL933, complete genomeATP-binding component of phosphonate transport3e-104377
CP002185:4566150:457401645740164574573558Escherichia coli W, complete genomeribose 1,5-bisphosphokinase3e-104376
NC_011748:4695932:470021347002134700770558Escherichia coli 55989, complete genomeribose 1,5-bisphosphokinase3e-104376
CU928145:4695932:470021347002134700770558Escherichia coli 55989 chromosome, complete genomeribose 1,5-bisphosphokinase3e-104376
NC_009801:4643000:464741146474114647968558Escherichia coli E24377A, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN3e-104376
CU928160:4395156:439943743994374399994558Escherichia coli IAI1 chromosome, complete genomeribose 1,5-bisphosphokinase3e-104376
NC_009800:4332229:434009543400954340652558Escherichia coli HS, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN3e-104376
NC_011415:4582388:458680745868074587364558Escherichia coli SE11 chromosome, complete genomeribose 1,5-bisphosphokinase3e-104376
NC_011741:4395156:439943743994374399994558Escherichia coli IAI1 chromosome, complete genomeribose 1,5-bisphosphokinase3e-104376
NC_013364:5040268:504813450481345048691558Escherichia coli O111:H- str. 11128, complete genomeribose 1,5-bisphosphokinase PhnN8e-104375
NC_007613:4156841:416472241647224165279558Shigella boydii Sb227, complete genomeATP-binding component of phosphonate transport2e-103374
NC_007606:3842708:385694138569413857498558Shigella dysenteriae Sd197, complete genomeATP-binding component of phosphonate transport1e-102372
NC_008563:4656000:466207246620724662629558Escherichia coli APEC O1, complete genomePhnN, ATP-binding component of phosphonate transport7e-102369
NC_011742:4569683:457660045766004577157558Escherichia coli S88 chromosome, complete genomeribose 1,5-bisphosphokinase7e-102369
NC_011751:4795928:480163148016314802188558Escherichia coli UMN026 chromosome, complete genomeribose 1,5-bisphosphokinase2e-101367
NC_011750:4719477:472379347237934724350558Escherichia coli IAI39 chromosome, complete genomeribose 1,5-bisphosphokinase3e-100363
NC_010498:4656716:466102246610224661579558Escherichia coli SMS-3-5, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN1e-99361
NC_008253:4541915:454813145481314548688558Escherichia coli 536, complete genomeATP-binding protein PhnN7e-99358
NC_012917:569856:570995570995571564570Pectobacterium carotovorum subsp. carotovorum PC1, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN6e-43173
NC_008740:257434:260167260167260736570Marinobacter aquaeolei VT8, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN2e-39161
NC_011770:1811874:181132618113261811883558Pseudomonas aeruginosa LESB58, complete genomeATP-binding component of phosphonate transport5e-36150
NC_008463:1756434:175759717575971758154558Pseudomonas aeruginosa UCBPP-PA14, complete genomeATP-binding component of phosphonate transport1e-35149
NC_008740:2563278:256693525669352567504570Marinobacter aquaeolei VT8, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN3e-35147
NC_007520:2305610:230676623067662307353588Thiomicrospira crunogena XCL-2, complete genomeGuanylate kinase/L-type calcium channel region2e-29128
NC_008786:3291700:330771633077163308282567Verminephrobacter eiseniae EF01-2, complete genomephosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN3e-26117
NC_003911:480202:480202480202480750549Silicibacter pomeroyi DSS-3, complete genomealkylphosphonate utilization protein PhnN7e-2096.7
NC_011206:1917408:192261119226111923156546Acidithiobacillus ferrooxidans ATCC 53993, complete genomehypothetical protein2e-1478.6
NC_011761:2031876:203707920370792037624546Acidithiobacillus ferrooxidans ATCC 23270 chromosome, completePhnN protein2e-1478.6
NC_009832:5369566:539044853904485391071624Serratia proteamaculans 568, complete genomeGuanylate kinase3e-0858.2
NC_020064:4751097:477073947707394771362624Serratia marcescens FGI94, complete genomeguanylate kinase4e-0857.8
NC_015846:493388:494751494751495323573Capnocytophaga canimorsus Cc5 chromosome, complete genomeGMP kinase3e-0755.1
NC_007912:4661141:468047146804714681148678Saccharophagus degradans 2-40, complete genomeGuanylate kinase4e-0754.3
NC_008800:36500:580715807158694624Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,guanylate kinase6e-0753.9
NC_011094:3778000:381826038182603818883624Salmonella enterica subsp. enterica serovar Schwarzengrund strguanylate kinase5e-0753.9
NC_015381:992401:101823010182301018904675Burkholderia gladioli BSR3 chromosome 1, complete sequenceguanylate kinase3e-0651.2
NC_016816:127802:130261130261130884624Pantoea ananatis LMG 5342, complete genomeguanylate kinase4e-0651.2
NC_013956:4326388:434381043438104344484675Pantoea ananatis LMG 20103 chromosome, complete genomeGmk4e-0651.2
NC_012731:5074000:509228450922845092964681Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeguanylate kinase4e-0651.2
NC_016845:5162481:518081651808165181439624Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,guanylate kinase5e-0650.8
NC_009648:4359875:437816143781614378784624Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeguanylate kinase5e-0650.8