Pre_GI: BLASTP Hits

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Query: NC_007384:4530000:4533904 Shigella sonnei Ss046, complete genome

Start: 4533904, End: 4534338, Length: 435

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:4686971:469083146908314691265435Shigella sonnei 53G, complete genomeaminoalkylphosphonic acid N-acetyltransferase9e-82301
NC_011748:4695932:469979246997924700226435Escherichia coli 55989, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-81300
CP002185:4566150:457359545735954574029435Escherichia coli W, complete genomepredicted acyltransferase with acyl-CoA N-acyltransferase domain2e-81300
CP002516:4431235:444506044450604445494435Escherichia coli KO11, complete genomeGCN5-related N-acetyltransferase2e-81300
NC_010473:4409492:441348944134894413923435Escherichia coli str. K-12 substr. DH10B, complete genomepredicted acyltransferase with acyl-CoA N-acyltransferase domain2e-81300
NC_011750:4719477:472337247233724723806435Escherichia coli IAI39 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-81300
CU928145:4695932:469979246997924700226435Escherichia coli 55989 chromosome, complete genomeputative acyltransferase with acyl-CoA N-acyltransferase domain2e-81300
NC_010498:4656716:466060146606014661035435Escherichia coli SMS-3-5, complete genomeacetyltransferase2e-81300
AP010958:5022196:502619350261935026627435Escherichia coli O103:H2 str. 12009 DNA, complete genomepredicted acyltransferase2e-81300
NC_000913:4307471:431312743131274313561435Escherichia coli K12, complete genomepredicted acyltransferase with acyl-CoA N-acyltransferase domain2e-81300
NC_009801:4643000:464699046469904647424435Escherichia coli E24377A, complete genomeacetyltransferase, GNAT family2e-81300
NC_010468:4305105:431842343184234318857435Escherichia coli ATCC 8739, complete genomeGCN5-related N-acetyltransferase2e-81300
NC_016902:4431235:444506044450604445494435Escherichia coli KO11FL chromosome, complete genomeN-acetyltransferase GCN52e-81300
NC_013364:5040268:504771350477135048147435Escherichia coli O111:H- str. 11128, complete genomeputative acyltransferase2e-81300
NC_013353:5022196:502619350261935026627435Escherichia coli O103:H2 str. 12009, complete genomeacyltransferase2e-81300
NC_012967:4289929:429392642939264294360435Escherichia coli B str. REL606 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-81300
NC_012947:4106031:411974841197484120182435Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeaminoalkylphosphonic acid N-acetyltransferase2e-81300
NC_012759:4247865:425186242518624252296435Escherichia coli BW2952 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-81300
NC_011415:4582388:458638645863864586820435Escherichia coli SE11 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-81300
AC_000091:4313167:431978243197824320216435Escherichia coli W3110 DNA, complete genomepredicted acyltransferase with acyl-CoA N-acyltransferase domain2e-81300
NC_011751:4795928:480121048012104801644435Escherichia coli UMN026 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase3e-81299
NC_008563:4656000:466165146616514662085435Escherichia coli APEC O1, complete genomePhnO, putative regulator of phn operon9e-81298
NC_011742:4569683:457617945761794576613435Escherichia coli S88 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase9e-81298
NC_009800:4332229:433967443396744340108435Escherichia coli HS, complete genomeacetyltransferase, GNAT family7e-81298
NC_013941:5013695:501882550188255019259435Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeacyltransferase with acyl-CoA N-acyltransferase domain6e-81298
NC_007606:3842708:385748538574853857919435Shigella dysenteriae Sd197, complete genomeputative regulator, phn operon2e-80297
CU928160:4395156:439901643990164399450435Escherichia coli IAI1 chromosome, complete genomeputative acyltransferase with acyl-CoA N-acyltransferase domain2e-80296
NC_011741:4395156:439901643990164399450435Escherichia coli IAI1 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase2e-80296
NC_008253:4541915:454771045477104548144435Escherichia coli 536, complete genomePhnO protein1e-79294
NC_004431:4867648:487414448741444874578435Escherichia coli CFT073, complete genomePhnO protein3e-79292
NC_007613:4156841:416428641642864164735450Shigella boydii Sb227, complete genomePhnO6e-78288
NC_002695:5164819:516995851699585170383426Escherichia coli O157:H7 str. Sakai, complete genomeputative phn operon regulator5e-77285
NC_011353:5240020:524515852451585245583426Escherichia coli O157:H7 str. EC4115 chromosome, complete genome5e-77285
NC_013008:5196080:520121952012195201644426Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeaminoalkylphosphonic acid N-acetyltransferase5e-77285
NC_002655:5194804:519994351999435200272330Escherichia coli O157:H7 EDL933, complete genomeputative regulator, phn operon2e-58223
NC_019897:938921:943680943680944111432Thermobacillus composti KWC4 chromosome, complete genomeacetyltransferase6e-1166.2
NC_020995:789665:813594813594814022429Enterococcus casseliflavus EC20, complete genomehypothetical protein2e-1064.7
NC_014623:6809000:682748968274896827953465Stigmatella aurantiaca DW4/3-1 chromosome, complete genomeacyl-CoA n-acyltransferase1e-0962
NC_013947:5682895:569440956944095694909501Stackebrandtia nassauensis DSM 44728 chromosome, complete genomeGCN5-related N-acetyltransferase1e-0961.6
NC_015424:2462522:246726824672682467717450Aeromonas veronii B565 chromosome, complete genomeGCN5-like N-acetyltransferase5e-0959.7
NC_016645:20199:350833508335556474Pyrobaculum sp. 1860 chromosome, complete genomeN-acyltransferase6e-0959.3
NC_016885:237682:251525251525251998474Pyrobaculum oguniense TE7 chromosome, complete genomeacetyltransferase3e-0753.5
NC_003364:951062:968042968042968515474Pyrobaculum aerophilum str. IM2, complete genomeN-acyltransferase4e-0753.5
NC_009376:1633283:164738916473891647862474Pyrobaculum arsenaticum DSM 13514 chromosome, complete genomeN-acetyltransferase GCN58e-0752.4
NC_016845:2729654:273012627301262730548423Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,acyltransferase domain-containing protein1e-0652
NC_015259:2757081:278291927829192783392474Polymorphum gilvum SL003B-26A1 chromosome, complete genomeAcetyltransferase, GNAT family1e-0651.6
NC_011283:2627050:265603326560332656455423Klebsiella pneumoniae 342 chromosome, complete genomeGNAT family acetyltransferase2e-0651.2
NC_013440:8405719:842861884286188429094477Haliangium ochraceum DSM 14365, complete genomeGCN5-related N-acetyltransferase2e-0651.2
NC_013850:2624899:265292526529252653347423Klebsiella variicola At-22 chromosome, complete genomeGCN5-related N-acetyltransferase2e-0650.8
NC_014831:866614:869776869776870234459Thermaerobacter marianensis DSM 12885 chromosome, complete genomeGCN5-related N-acetyltransferase3e-0650.4
NC_009659:543000:558995558995559588594Janthinobacterium sp. Marseille chromosome, complete genomeacetyltransferase4e-0650.1
NC_015850:110364:159381159381159866486Acidithiobacillus caldus SM-1 chromosome, complete genomeGCN5-like N-acetyltransferase8e-0649.3
NC_015145:92397:986909869099139450Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genomeGNAT family acetyltransferase9e-0648.9