Pre_GI: BLASTP Hits

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Query: NC_007384:4530000:4532668 Shigella sonnei Ss046, complete genome

Start: 4532668, End: 4532997, Length: 330

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016902:4431235:444640144464014446730330Escherichia coli KO11FL chromosome, complete genomehypothetical protein2e-21100
CP002516:4431235:444640144464014446730330Escherichia coli KO11, complete genomehypothetical protein2e-21100
AP010958:5022196:502495750249575025286330Escherichia coli O103:H2 str. 12009 DNA, complete genomehypothetical protein2e-21100
NC_004431:4867648:487302748730274873356330Escherichia coli CFT073, complete genomehypothetical protein2e-21100
NC_009801:4643000:464575446457544646083330Escherichia coli E24377A, complete genomehypothetical protein2e-21100
AC_000091:4313167:431854643185464318875330Escherichia coli W3110 DNA, complete genomehypothetical protein2e-21100
NC_008253:4541915:454659345465934546922330Escherichia coli 536, complete genomehypothetical protein2e-21100
NC_000913:4307471:431189143118914312220330Escherichia coli K12, complete genomehypothetical protein2e-21100
CU928160:4395156:439778043977804398109330Escherichia coli IAI1 chromosome, complete genomeconserved hypothetical protein2e-21100
NC_007613:4156841:416305041630504163379330Shigella boydii Sb227, complete genomehypothetical protein2e-21100
CP002185:4566150:457235945723594572688330Escherichia coli W, complete genomehypothetical protein2e-21100
CU928145:4695932:469855646985564698885330Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein2e-21100
NC_016822:4686971:468959546895954689924330Shigella sonnei 53G, complete genomehypothetical protein2e-21100
NC_013364:5040268:504647750464775046806330Escherichia coli O111:H- str. 11128, complete genomehypothetical protein2e-21100
NC_013353:5022196:502495750249575025286330Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein2e-21100
NC_012967:4289929:429269042926904293019330Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein2e-21100
NC_012759:4247865:425062642506264250955330Escherichia coli BW2952 chromosome, complete genomehypothetical protein2e-21100
NC_011741:4395156:439778043977804398109330Escherichia coli IAI1 chromosome, complete genomehypothetical protein2e-21100
NC_011415:4582388:458515045851504585479330Escherichia coli SE11 chromosome, complete genomehypothetical protein2e-21100
NC_010473:4409492:441225344122534412582330Escherichia coli str. K-12 substr. DH10B, complete genomehypothetical protein2e-21100
NC_011748:4695932:469855646985564698885330Escherichia coli 55989, complete genomehypothetical protein2e-21100
NC_008563:4656000:466053446605344660863330Escherichia coli APEC O1, complete genomehypothetical protein5e-2199.8
NC_011742:4569683:457506245750624575391330Escherichia coli S88 chromosome, complete genomehypothetical protein5e-2199.8
NC_011751:4795928:480008648000864800415330Escherichia coli UMN026 chromosome, complete genomehypothetical protein6e-2199.4
NC_012947:4106031:412108941210894121418330Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein7e-2199
NC_010468:4305105:431976443197644320093330Escherichia coli ATCC 8739, complete genomehypothetical protein7e-2199
NC_011750:4719477:472223947222394722577339Escherichia coli IAI39 chromosome, complete genomehypothetical protein3e-1993.6
NC_010498:4656716:465947746594774659806330Escherichia coli SMS-3-5, complete genomehypothetical protein5e-1993.2
NC_013941:5013695:501765950176595017988330Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein4e-1890.1
NC_011353:5240020:524399352439935244280288Escherichia coli O157:H7 str. EC4115 chromosome, complete genome4e-1890.1
NC_013008:5196080:520005352000535200382330Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein5e-1889.7
NC_002655:5194804:519877751987775199106330Escherichia coli O157:H7 EDL933, complete genomehypothetical protein5e-1889.7
NC_002695:5164819:516879251687925169121330Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein5e-1889.7
NC_007606:3842708:385875638587563859085330Shigella dysenteriae Sd197, complete genomeZ5694-like protein1e-1788.2