Pre_GI: BLASTP Hits

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Query: NC_007384:3956465:3957578 Shigella sonnei Ss046, complete genome

Start: 3957578, End: 3958057, Length: 480

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:4093000:409443840944384094917480Shigella sonnei 53G, complete genomephosphopantetheine adenylyltransferase4e-90329
NC_002655:4606000:462266746226674623146480Escherichia coli O157:H7 EDL933, complete genomephosphopantetheine adenylyltransferase4e-89326
CP002516:88500:899008990090379480Escherichia coli KO11, complete genomepantetheine-phosphate adenylyltransferase4e-89326
CU928160:3862935:388050838805083880987480Escherichia coli IAI1 chromosome, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_007613:3637832:365542336554233655902480Shigella boydii Sb227, complete genomeputative enzyme of lipopolysaccharide synthesis4e-89326
NC_009801:4108179:412576141257614126240480Escherichia coli E24377A, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_004337:3761865:378013937801393780618480Shigella flexneri 2a str. 301, complete genomephosphopantetheine adenylyltransferase4e-89326
CP002185:3998112:401569440156944016173480Escherichia coli W, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_004337:3590323:378013937801393780618480Shigella flexneri 2a str. 301, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_000913:3786124:380784838078483808327480Escherichia coli K12, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_008258:3995553:399776939977693998248480Shigella flexneri 5 str. 8401, complete genomeputative enzyme of lipopolysaccharide synthesis4e-89326
NC_011748:4167043:418484741848474185326480Escherichia coli 55989, complete genomephosphopantetheine adenylyltransferase4e-89326
CU928145:4167043:418484741848474185326480Escherichia coli 55989 chromosome, complete genomepantetheine-phosphate adenylyltransferase4e-89326
AP010958:4668181:467043646704364670915480Escherichia coli O103:H2 str. 12009 DNA, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_002695:4537000:455368445536844554163480Escherichia coli O157:H7 str. Sakai, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_010658:3774110:379264737926473793126480Shigella boydii CDC 3083-94, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_009800:3821824:383940638394063839885480Escherichia coli HS, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_010468:80000:814718147181950480Escherichia coli ATCC 8739, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_010473:3883701:390542539054253905904480Escherichia coli str. K-12 substr. DH10B, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_017328:3794105:381233938123393812818480Shigella flexneri 2002017 chromosome, complete genomePhosphopantetheine adenylyltransferase4e-89326
NC_016902:88500:899008990090379480Escherichia coli KO11FL chromosome, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_013941:4427000:444362944436294444108480Escherichia coli O55:H7 str. CB9615 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_013364:4460500:447722644772264477705480Escherichia coli O111:H- str. 11128, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_013361:4991020:499327549932754993754480Escherichia coli O26:H11 str. 11368 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_013353:4668181:467043646704364670915480Escherichia coli O103:H2 str. 12009, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_013008:4595043:461282946128294613308480Escherichia coli O157:H7 str. TW14359 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_012967:3729813:374818037481803748659480Escherichia coli B str. REL606 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_012947:94930:957789577896257480Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completephosphopantetheine adenylyltransferase4e-89326
AC_000091:3827856:383011138301113830590480Escherichia coli W3110 DNA, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_004741:3992384:399463939946393995118480Shigella flexneri 2a str. 2457T, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_010498:4031500:404784640478464048325480Escherichia coli SMS-3-5, complete genomepantetheine-phosphate adenylyltransferase4e-89326
NC_011353:4639002:465678846567884657267480Escherichia coli O157:H7 str. EC4115 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_011415:4040211:405801540580154058494480Escherichia coli SE11 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_011741:3862935:388050838805083880987480Escherichia coli IAI1 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_012759:3675396:369617436961743696653480Escherichia coli BW2952 chromosome, complete genomephosphopantetheine adenylyltransferase4e-89326
NC_004431:4223232:424082342408234241302480Escherichia coli CFT073, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_008253:3896704:391429539142953914774480Escherichia coli 536, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_011751:4251296:426910342691034269582480Escherichia coli UMN026 chromosome, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_007946:4050762:406835340683534068832480Escherichia coli UTI89, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_011742:3998285:401587640158764016355480Escherichia coli S88 chromosome, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_011745:4226186:424398942439894244468480Escherichia coli ED1a chromosome, complete genomephosphopantetheine adenylyltransferase2e-88324
NC_011740:4007000:402653640265364027015480Escherichia fergusonii ATCC 35469, complete genomepantetheine-phosphate adenylyltransferase3e-88323
NC_011601:4036590:405619540561954056674480Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomephosphopantetheine adenylyltransferase7e-88322
NC_011750:4307166:432474543247454325224480Escherichia coli IAI39 chromosome, complete genomephosphopantetheine adenylyltransferase6e-88322
NC_007606:3784847:380209438020943802573480Shigella dysenteriae Sd197, complete genomeputative enzyme of LPS biosynthesis4e-87319
NC_009792:4658909:467509646750964675575480Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein2e-84310
NC_003197:3902500:392062439206243921103480Salmonella typhimurium LT2, complete genomephosphopantetheine adenylyltransferase2e-83307
NC_016810:3923988:394193839419383942417480Salmonella enterica subsp. enterica serovar Typhimurium strphosphopantetheine adenylyltransferase2e-83307
NC_016856:3916500:393431639343163934795480Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sphosphopantetheine adenylyltransferase2e-83307
NC_016857:3924000:394193939419393942418480Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74phosphopantetheine adenylyltransferase2e-83307
NC_016860:3925500:394352039435203943999480Salmonella enterica subsp. enterica serovar Typhimurium strphosphopantetheine adenylyltransferase2e-83307
NC_016863:3864000:388192338819233882402480Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1phosphopantetheine adenylyltransferase2e-83307
NC_017046:3923000:394076539407653941244480Salmonella enterica subsp. enterica serovar Typhimurium str. 798phosphopantetheine adenylyltransferase2e-83307
NC_011149:3822000:383999138399913840470480Salmonella enterica subsp. enterica serovar Agona str. SL483,pantetheine-phosphate adenylyltransferase3e-83306
NC_010102:3851500:386957138695713870050480Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein7e-83305
NC_011080:3875320:389377538937753894254480Salmonella enterica subsp. enterica serovar Newport str. SL254,pantetheine-phosphate adenylyltransferase7e-83305
NC_011083:3915500:393363439336343934113480Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,pantetheine-phosphate adenylyltransferase7e-83305
NC_011094:3778000:379671037967103797189480Salmonella enterica subsp. enterica serovar Schwarzengrund strphosphopantetheine adenylyltransferase7e-83305
NC_011205:3942500:396032539603253960804480Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853phosphopantetheine adenylyltransferase7e-83305
NC_011274:3894387:389662938966293897108480Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91phosphopantetheine adenylyltransferase7e-83305
NC_011294:3782655:380172838017283802207480Salmonella enterica subsp. enterica serovar Enteritidis strphosphopantetheine adenylyltransferase7e-83305
NC_016831:3875134:387737638773763877855480Salmonella enterica subsp. enterica serovar Gallinarum/pullorumphosphopantetheine adenylyltransferase7e-83305
NC_003198:3924952:392719439271943927673480Salmonella enterica subsp. enterica serovar Typhi str. CT18,phosphopantetheine adenylyltransferase1e-82304
NC_004631:3910451:391269339126933913172480Salmonella enterica subsp. enterica serovar Typhi Ty2, completephosphopantetheine adenylyltransferase1e-82304
NC_006511:3690828:370928337092833709762480Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCphosphopantetheine adenylyltransferase1e-82304
NC_011147:3686500:370496037049603705439480Salmonella enterica subsp. enterica serovar Paratyphi A strphosphopantetheine adenylyltransferase1e-82304
NC_016832:3900000:390149039014903901969480Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Phosphopantetheine adenylyltransferase1e-82304
NC_015761:3611993:363045136304513630930480Salmonella bongori NCTC 12419, complete genomephosphopantetheine adenylyltransferase3e-82303
NC_006905:3845000:386292538629253863404480Salmonella enterica subsp. enterica serovar Choleraesuis strphosphopantetheine adenylyltransferase6e-82302
NC_012125:3840000:385778038577803858259480Salmonella enterica subsp. enterica serovar Paratyphi C strainphosphopantetheine adenylyltransferase6e-82302
NC_010067:3846962:384806038480603848539480Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein4e-81299
NC_013716:4408201:441055544105554411034480Citrobacter rodentium ICC168, complete genomephosphopantetheine adenylyltransferase7e-81298
NC_020063:97436:982839828398762480Enterobacteriaceae bacterium strain FGI 57, complete genomepantetheine-phosphate adenylyltransferase2e-79294
NC_011283:105245:124357124357124836480Klebsiella pneumoniae 342 chromosome, complete genomephosphopantetheine adenylyltransferase1e-76284
NC_013850:109500:129557129557130036480Klebsiella variicola At-22 chromosome, complete genomepantetheine-phosphate adenylyltransferase1e-76284
NC_016816:127802:148602148602149081480Pantoea ananatis LMG 5342, complete genomepantetheine-phosphate adenylyltransferase2e-69260
NC_013971:73037:104967104967105443477Erwinia amylovora ATCC 49946 chromosome, complete genomephosphopantetheine adenylyltransferase3e-67253
NC_013961:73037:104967104967105443477Erwinia amylovora, complete genomePhosphopantetheine adenylyltransferase3e-67253
NC_004547:164000:170375170375170854480Erwinia carotovora subsp. atroseptica SCRI1043, complete genomephosphopantetheine adenylyltransferase2e-66251
NC_013421:4790696:480892348089234809414492Pectobacterium wasabiae WPP163, complete genomepantetheine-phosphate adenylyltransferase3e-66250
NC_016745:675909:679702679702680187486Oceanimonas sp. GK1 chromosome, complete genomephosphopantetheine adenylyltransferase4e-58223
NC_008577:4907497:491465449146544915145492Shewanella sp. ANA-3 chromosome 1, complete sequencepantetheine-phosphate adenylyltransferase3e-57220
NC_008321:4631866:463902246390224639513492Shewanella sp. MR-4, complete genomepantetheine-phosphate adenylyltransferase3e-57220
NC_009052:71058:805748057481065492Shewanella baltica OS155, complete genomepantetheine-phosphate adenylyltransferase3e-55213
NC_003919:2956404:295923929592392959745507Xanthomonas axonopodis pv. citri str. 306, complete genomephosphopantetheine adenylyltransferase8e-51199
NC_007508:3065621:306845630684563068962507Xanthomonas campestris pv. vesicatoria str. 85-10, complete genomephosphopantetheine adenylyltransferase1e-50198
NC_010688:2052619:207007620700762070582507Xanthomonas campestris pv. campestris, complete genomePantetheine-phosphate adenylyltransferase1e-49194
NC_015672:101878:119390119390119863474Flexistipes sinusarabici DSM 4947 chromosome, complete genomephosphopantetheine adenylyltransferase3e-48190
NC_014532:3479674:350659035065903507069480Halomonas elongata DSM 2581, complete genomephosphopantetheine adenylyltransferase2e-46184
NC_013939:148706:161437161437161925489Deferribacter desulfuricans SSM1, complete genomephosphopantetheine adenylyltransferase2e-46184
NC_008344:2465042:246724024672402467734495Nitrosomonas eutropha C91, complete genomepantetheine-phosphate adenylyltransferase3e-44177
NC_010084:534937:540918540918541415498Burkholderia multivorans ATCC 17616 chromosome 1, completephosphopantetheine adenylyltransferase1e-43175
NC_007404:387827:408401408401408883483Thiobacillus denitrificans ATCC 25259, complete genomepanththeine-phosphate adenylyltransferase3e-42170
NC_014964:1309845:132980413298041330283480Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completepantetheine-phosphate adenylyltransferase3e-42170
NC_017187:937649:939440939440939934495Arcobacter butzleri ED-1, complete genomephosphopantetheine adenylyltransferase5e-42169
NC_011653:1339868:137909513790951379571477Thermosipho africanus TCF52B, complete genomepantetheine-phosphate adenylyltransferase1e-41168
NC_015958:1422319:144161714416171442099483Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomephosphopantetheine adenylyltransferase1e-41168
NC_009850:972692:974483974483974977495Arcobacter butzleri RM4018, complete genomephosphopantetheine adenylyltransferase2e-41167
NC_018664:1729794:173491017349101735395486Clostridium acidurici 9a chromosome, complete genomePhosphopantetheine adenylyltransferase CoaD3e-41167
NC_014248:943198:957291957291957842552Nostoc azollae 0708 chromosome, complete genomepantetheine-phosphate adenylyltransferase6e-41166
NC_014831:1140356:113986811398681140359492Thermaerobacter marianensis DSM 12885 chromosome, complete genomePhosphopantetheine adenylyltransferase6e-40162
NC_017280:689067:714677714677715153477Campylobacter jejuni subsp. jejuni M1 chromosome, complete genomePhosphopantetheine adenylyltransferase9e-40162
NC_011365:592256:598970598970599479510Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genomepantetheine-phosphate adenylyltransferase1e-39161
NC_014622:2114244:211972921197292120250522Paenibacillus polymyxa SC2 chromosome, complete genomephosphopantetheine adenylyltransferase4e-39160
NC_013385:90331:104996104996105496501Ammonifex degensii KC4, complete genomepantetheine-phosphate adenylyltransferase1e-38159
NC_014483:1954856:196032119603211960842522Paenibacillus polymyxa E681 chromosome, complete genomePhosphopantetheine adenylyltransferase (Pantetheine-phosphate adenylyltransferase)7e-39159
NC_009718:731670:731670731670732152483Fervidobacterium nodosum Rt17-B1, complete genomephosphopantetheine adenylyltransferase2e-38157
NC_011661:1143787:116144911614491161931483Dictyoglomus turgidum DSM 6724, complete genomepantetheine-phosphate adenylyltransferase3e-38157
NS_000195:1257834:127712312771231277602480Candidatus Cloacamonas acidaminovoransPhosphopantetheine adenylyltransferase (Pantetheine-phosphate adenylyltransferase) (PPAT) (Dephospho-CoA pyrophosphorylase)5e-38156
NC_009828:469778:485320485320485814495Thermotoga lettingae TMO, complete genomepantetheine-phosphate adenylyltransferase9e-38155
NC_002937:1578213:160029916002991600859561Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completepantetheine-phosphate adenylyltransferase3e-37154
NC_020409:363114:375923375923376441519Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completePhosphopantetheine adenylyltransferase3e-37154
NC_007799:727798:746771746771747268498Ehrlichia chaffeensis str. Arkansas, complete genomepantetheine-phosphate adenylyltransferase4e-37153
NC_002976:707827:710235710235710720486Staphylococcus epidermidis RP62A, complete genomepantetheine-phosphate adenylyltransferase2e-36151
NC_004461:813748:816156816156816641486Staphylococcus epidermidis ATCC 12228, complete genomephosphopantetheine adenyltransferase-like protein2e-36151
NC_009699:2654672:267804626780462678540495Clostridium botulinum F str. Langeland chromosome, complete genomephosphopantetheine adenylyltransferase3e-36150
NC_007907:1547539:155113815511381551629492Desulfitobacterium hafniense Y51, complete genomehypothetical protein4e-36150
NC_010730:180000:197728197728198231504Sulfurihydrogenibium sp. YO3AOP1, complete genomepantetheine-phosphate adenylyltransferase1e-34145
NC_008278:6279553:629133062913306291818489Frankia alni ACN14a, complete genomeCMP-deoxy-D-manno-octulosonate-lipid A transferase (phosphopantetheine adenylyltransferase)1e-34145
NC_013517:2633574:263357426335742634074501Sebaldella termitidis ATCC 33386, complete genomepantetheine-phosphate adenylyltransferase2e-33140
NC_009484:1299500:131330313133031313812510Acidiphilium cryptum JF-5 chromosome, complete genomepantetheine-phosphate adenylyltransferase8e-33139
NC_005956:1111500:112001911200191120552534Bartonella henselae str. Houston-1, complete genomephosphopantetheine adenylyltransferase2e-31134
NC_014221:591785:611246611246611737492Truepera radiovictrix DSM 17093 chromosome, complete genomepantetheine-phosphate adenylyltransferase8e-31132
NC_010161:1501758:152831715283171528823507Bartonella tribocorum CIP 105476, complete genomephosphopantetheine adenylyltransferase6e-31132
NC_014960:1697818:170284117028411703356516Anaerolinea thermophila UNI-1, complete genomephosphopantetheine adenylyltransferase1e-30131
NC_014550:1581812:164954416495441650011468Arthrobacter arilaitensis Re117, complete genomepantetheine-phosphate adenylyltransferase2e-29128
NC_015177:258504:263379263379263852474Pedobacter saltans DSM 12145 chromosome, complete genomepantetheine-phosphate adenylyltransferase6e-29126
NC_020054:3501467:350456935045693505027459Fibrella aestuarina BUZ 2 drat genomepantetheine-phosphate adenylyltransferase2e-28124
NC_021064:816000:835065835065835541477Propionibacterium avidum 44067, complete genomephosphopantetheine adenylyltransferase3e-28124
NC_006448:1451729:146189814618981462395498Streptococcus thermophilus LMG 18311, complete genomephosphopantetheine adenylyltransferase3e-28124
NC_015703:4348545:436737943673794367852474Runella slithyformis DSM 19594 chromosome, complete genomephosphopantetheine adenylyltransferase2e-27121
NC_014752:324832:327715327715328227513Neisseria lactamica ST-640, complete genomelipopolysaccharide core biosynthesis protein3e-27120
NC_016633:541559:541062541062541562501Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomepantetheine-phosphate adenylyltransferase1e-25115
NC_008710:703740:744246744246744743498Borrelia turicatae 91E135, complete genomephosphopantetheine adenylyltransferase8e-25112
NC_010673:703816:747004747004747501498Borrelia hermsii DAH, complete genomephosphopantetheine adenylyltransferase1e-24112
NC_011244:746801:758528758528759025498Borrelia recurrentis A1, complete genomephosphopantetheine adenylyltransferase1e-23108
NC_007294:734647:756186756186756617432Mycoplasma synoviae 53, complete genomeputative pantetheine-phosphate adenylyltransferase6e-23106
NC_004663:3827521:384188838418883842343456Bacteroides thetaiotaomicron VPI-5482, complete genomephosphopantetheine adenylyltransferase2e-21101
NC_015434:1313979:132781313278131328271459Verrucosispora maris AB-18-032 chromosome, complete genomephosphopantetheine adenylyltransferase6e-2096.7