Pre_GI: BLASTP Hits

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Query: NC_007384:307013:322849 Shigella sonnei Ss046, complete genome

Start: 322849, End: 323256, Length: 408

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010473:1384000:138989113898911390772882Escherichia coli str. K-12 substr. DH10B, complete genome2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase2e-66250
NC_014118:987889:994558994558995427870Burkholderia sp. CCGE1002 chromosome chromosome 2, completealpha/beta hydrolase fold protein5e-32135
NC_016147:1825827:184396218439621844786825Pseudoxanthomonas spadix BD-a59 chromosome, complete genome2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase2e-22103
NC_008726:4725389:473718447371844738017834Mycobacterium vanbaalenii PYR-1, complete genomealpha/beta hydrolase fold1e-1684.7
NC_009511:4582188:460471046047104605549840Sphingomonas wittichii RW1 chromosome, complete genomealpha/beta hydrolase fold protein4e-1683.2
NC_008595:2546696:255055025505502551422873Mycobacterium avium 104, complete genome2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase4e-1580.1
NC_018697:505915:524287524287525117831Cycloclasticus sp. P1 chromosome, complete genomeAlpha/beta hydrolase fold protein2e-1064.7
NC_015690:8614000:862439786243978625233837Paenibacillus mucilaginosus KNP414 chromosome, complete genomePutative non-heme chloroperoxidase2e-0960.8
NC_007973:1411714:142115514211551421985831Ralstonia metallidurans CH34 chromosome 1, complete sequencealpha/beta hydrolase fold2e-0960.8
NC_014118:987889:100575610057561006601846Burkholderia sp. CCGE1002 chromosome chromosome 2, completealpha/beta hydrolase fold protein3e-0960.5
NC_016147:1788219:180525318052531806083831Pseudoxanthomonas spadix BD-a59 chromosome, complete genomealpha/beta hydrolase fold protein1e-0858.9
NC_017506:1100679:113944911394491140309861Marinobacter adhaerens HP15 chromosome, complete genome2-hydroxymuconic semialdehyde hydrolase3e-0857.4
NC_014098:2332938:235608723560872356923837Bacillus tusciae DSM 2912 chromosome, complete genomealpha/beta hydrolase fold protein5e-0856.6
NC_021150:4201965:4208063420806342091751113Azotobacter vinelandii CA6, complete genomebranched-chain alpha-keto acid dehydrogenase subunit E25e-0856.6
NC_012560:4201969:4208067420806742091791113Azotobacter vinelandii DJ, complete genomedihydrolipoamide acetyltransferase,acetoin dehydrogeanse E2 component, AcoC5e-0856.6
NC_010505:5583000:560222456022245603045822Methylobacterium radiotolerans JCM 2831, complete genomealpha/beta hydrolase fold5e-0856.6
NC_011666:1572487:158471515847151585554840Methylocella silvestris BL2, complete genomealpha/beta hydrolase fold protein8e-0855.8
NC_014019:3543389:354338935433893544225837Bacillus megaterium QM B1551 chromosome, complete genomehydrolase, alpha/beta fold family1e-0755.1
NC_010170:3944228:394663739466373947467831Bordetella petrii, complete genome2-hydroxy-6-phenylhexa-2,4-dienoic acid hydrolase2e-0754.7
NC_017507:155938:1593461593461603831038Marinobacter adhaerens HP15 plasmid pHP-187, complete sequencealpha/beta hydrolase fold protein2e-0754.7
NC_017192:2505369:252556425255642526385822Arcobacter sp. L, complete genome2-hydroxymuconic semialdehyde hydrolase2e-0754.3
NC_002927:4392768:439380943938094394624816Bordetella bronchiseptica RB50, complete genomeputative hydrolase3e-0753.9
NC_010943:493002:517556517556518368813Stenotrophomonas maltophilia K279a, complete genomeputative arylesterase (aryl-ester hydrolase)3e-0753.9
NC_007348:2519447:252089825208982521749852Ralstonia eutropha JMP134 chromosome 2, complete sequenceAlpha/beta hydrolase fold4e-0753.5
NC_009664:4423829:458113745811374581973837Kineococcus radiotolerans SRS30216, complete genomealpha/beta hydrolase fold5e-0753.1
NC_009512:3251545:327318632731863274016831Pseudomonas putida F1, complete genomealpha/beta hydrolase fold5e-0753.1
NC_009512:1518113:152055915205591521371813Pseudomonas putida F1, complete genomealpha/beta hydrolase fold8e-0752.4
NC_015947:444466:462021462021462833813Burkholderia sp. JV3 chromosome, complete genomeChloride peroxidase1e-0652.4
NC_016605:1177485:119659611965961197375780Pediococcus claussenii ATCC BAA-344 chromosome, complete genomealpha/beta hydrolase fold family protein2e-0651.6
NC_007412:110698:128094128094128954861Anabaena variabilis ATCC 29413 plasmid C, complete sequenceAlpha/beta hydrolase fold2e-0651.2
NC_007298:1418500:144876914487691449605837Dechloromonas aromatica RCB, complete genomeAlpha/beta hydrolase fold3e-0650.8
NC_014098:2332938:234743423474342348261828Bacillus tusciae DSM 2912 chromosome, complete genomealpha/beta hydrolase fold protein3e-0650.4
NC_008705:4053070:405965340596534060501849Mycobacterium sp. KMS, complete genomealpha/beta hydrolase fold4e-0650.4
NC_008146:4019711:402517140251714026019849Mycobacterium sp. MCS, complete genomealpha/beta hydrolase fold4e-0650.4
NC_016147:2964178:297355829735582974382825Pseudoxanthomonas spadix BD-a59 chromosome, complete genomemeta cleavage compound hydrolase4e-0650.1
NC_011832:2306341:230744823074482308293846Candidatus Methanosphaerula palustris E1-9c, complete genomealpha/beta hydrolase fold protein5e-0650.1
NC_016830:530397:537455537455538417963Pseudomonas fluorescens F113 chromosome, complete genomealpha beta hydrolase fold protein5e-0649.7
NC_015216:1647462:166207616620761662903828Methanobacterium sp. AL-21 chromosome, complete genomechloride peroxidase6e-0649.7