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Query: NC_007384:2933625:2942664 Shigella sonnei Ss046, complete genome

Start: 2942664, End: 2944142, Length: 1479

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:3065426:3073968307396830754461479Shigella sonnei 53G, complete genomehypothetical protein0899
NC_011751:3048490:3085706308570630871601455Escherichia coli UMN026 chromosome, complete genomehypothetical protein0725
NC_010473:2839902:2873425287342528747981374Escherichia coli str. K-12 substr. DH10B, complete genome0649
NC_002655:3538656:3573136357313635744851350Escherichia coli O157:H7 EDL933, complete genomehypothetical protein3e-175615
NC_002695:3468873:3505846350584635071951350Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein3e-175615
NC_011353:3573641:3610082361008236114311350Escherichia coli O157:H7 str. EC4115 chromosome, complete genome3e-175615
NC_013008:3525428:3564807356480735661561350Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein3e-175615
NC_013941:3300000:3343590334359033449391350Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein4e-175614
NC_010498:2847359:285718428571842857933750Escherichia coli SMS-3-5, complete genomehypothetical protein5e-118425
NC_011750:2928990:294979329497932950527735Escherichia coli IAI39 chromosome, complete genome1e-113410
AC_000091:2747520:278229427822942783085792Escherichia coli W3110 DNA, complete genomehypothetical protein2e-102373
NC_000913:2746886:278166027816602782451792Escherichia coli K12, complete genomehypothetical protein2e-102373
CU928160:2818750:282847028284702829213744Escherichia coli IAI1 chromosome, complete genomefragment of conserved hypothetical protein from bacteriophage origin (part 2)8e-102371
NC_011741:2818750:282847028284702829213744Escherichia coli IAI1 chromosome, complete genome8e-102371
CU928145:2973968:299425429942542994943690Escherichia coli 55989 chromosome, complete genomefragment of conserved hypothetical protein from bacteriophage origin (part 2)2e-92340
NC_011748:2973968:299425429942542994943690Escherichia coli 55989, complete genome2e-92340
NC_011741:2818750:282922828292282829842615Escherichia coli IAI1 chromosome, complete genome1e-87323
CU928160:2818750:282922828292282829842615Escherichia coli IAI1 chromosome, complete genomefragment of conserved hypothetical protein from bacteriophage origin (part 1)1e-87323
NC_010468:1130000:1139159113915911405301372Escherichia coli ATCC 8739, complete genome3e-82306
AC_000091:2747520:278318527831852783667483Escherichia coli W3110 DNA, complete genomehypothetical protein7e-60231
NC_000913:2746886:278255127825512783033483Escherichia coli K12, complete genomehypothetical protein7e-60231
CU928145:2973968:299514429951442995626483Escherichia coli 55989 chromosome, complete genomefragment of conserved hypothetical protein from bacteriophage origin (part 1)7e-60231
NC_009800:2788164:280074328007432801225483Escherichia coli HS, complete genomeconserved hypothetical protein, truncation7e-60231
NC_011748:2973968:299514429951442995626483Escherichia coli 55989, complete genome7e-60231
NC_010498:2847359:285826728582672858623357Escherichia coli SMS-3-5, complete genome1e-51204
NC_011750:2928990:295075329507532951109357Escherichia coli IAI39 chromosome, complete genome2e-51204