Pre_GI: BLASTP Hits

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Query: NC_007384:2587876:2606935 Shigella sonnei Ss046, complete genome

Start: 2606935, End: 2607558, Length: 624

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017328:2516000:253447225344722535095624Shigella flexneri 2002017 chromosome, complete genomehypothetical protein8e-106382
NC_016822:2678691:269775026977502698373624Shigella sonnei 53G, complete genomehypothetical protein8e-106382
NC_004337:2478461:249683024968302497453624Shigella flexneri 2a str. 301, complete genomehypothetical protein8e-106382
NC_004741:2456297:247496824749682475591624Shigella flexneri 2a str. 2457T, complete genomehypothetical protein8e-106382
NC_008258:2473000:249057024905702491193624Shigella flexneri 5 str. 8401, complete genomehypothetical protein8e-106382
NC_010468:1412791:141668414166841417316633Escherichia coli ATCC 8739, complete genomehypothetical protein5e-104376
NC_010658:2529033:254846425484642549096633Shigella boydii CDC 3083-94, complete genomehypothetical protein5e-104376
NC_009801:2639787:265727626572762657908633Escherichia coli E24377A, complete genomehypothetical protein5e-104376
NC_007606:2353098:237099623709962371628633Shigella dysenteriae Sd197, complete genomehypothetical protein5e-104376
CP002516:1419413:142699914269991427631633Escherichia coli KO11, complete genomehypothetical protein5e-104376
NC_007613:2376974:239569923956992396331633Shigella boydii Sb227, complete genomehypothetical protein5e-104376
CP002185:2659628:267822626782262678858633Escherichia coli W, complete genomepredicted protein5e-104376
CU928160:2513000:253063725306372531269633Escherichia coli IAI1 chromosome, complete genomeconserved hypothetical protein5e-104376
AP010958:2911741:294476429447642945396633Escherichia coli O103:H2 str. 12009 DNA, complete genomeconserved predicted protein5e-104376
NC_016902:1419413:142699914269991427631633Escherichia coli KO11FL chromosome, complete genomehypothetical protein5e-104376
NC_013353:2911741:294476429447642945396633Escherichia coli O103:H2 str. 12009, complete genomehypothetical protein5e-104376
NC_012967:2409500:242799424279942428626633Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein5e-104376
NC_012947:1363724:136761713676171368249633Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein5e-104376
NC_011741:2513000:253063725306372531269633Escherichia coli IAI1 chromosome, complete genomehypothetical protein5e-104376
NC_009800:2505872:252517225251722525804633Escherichia coli HS, complete genomehypothetical protein5e-104376
NC_013941:2928000:296297029629702963605636Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein1e-103375
NC_011742:2533500:255066625506662551301636Escherichia coli S88 chromosome, complete genomehypothetical protein1e-103375
NC_008563:2610499:262757126275712628206636Escherichia coli APEC O1, complete genomehypothetical protein1e-103375
NC_011745:2751437:276850927685092769141633Escherichia coli ED1a chromosome, complete genomehypothetical protein1e-103375
NC_011601:2614691:265017926501792650811633Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomehypothetical protein3e-103374
NC_011751:2768864:278635127863512786983633Escherichia coli UMN026 chromosome, complete genomehypothetical protein2e-103374
NC_011353:3276734:332601633260163326651636Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein4e-103373
NC_008253:2499735:251720125172012517668468Escherichia coli 536, complete genomeYfdX protein precursor6e-85313
NC_009648:3803622:384145338414533842115663Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomehypothetical protein8e-54209
NC_004631:3030580:303527330352733035872600Salmonella enterica subsp. enterica serovar Typhi Ty2, completehypothetical protein1e-37156
NC_003198:3042000:304936630493663049965600Salmonella enterica subsp. enterica serovar Typhi str. CT18,hypothetical protein1e-37156
NC_016832:3020000:302391330239133024545633Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein1e-37156
NC_011083:3171171:317508031750803175712633Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,YfdX protein8e-38156
NC_012721:240000:240629240629241309681Burkholderia glumae BGR1 chromosome 2, complete genomehypothetical protein2e-1479
NC_015381:3091500:309537030953703096050681Burkholderia gladioli BSR3 chromosome 1, complete sequencehypothetical protein1e-1170.1
NC_013851:949973:956936956936957790855Allochromatium vinosum DSM 180 chromosome, complete genomehypothetical protein1e-0756.6