Pre_GI: BLASTP Hits

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Query: NC_007384:2587876:2592370 Shigella sonnei Ss046, complete genome

Start: 2592370, End: 2593698, Length: 1329

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:2678691:2683185268318526845131329Shigella sonnei 53G, complete genomeD-serine dehydratase0893
CP002185:2659628:2663661266366126649891329Escherichia coli W, complete genomeD-serine ammonia-lyase0891
NC_010473:2548946:2568989256898925703171329Escherichia coli str. K-12 substr. DH10B, complete genomeD-serine ammonia-lyase0891
NC_000913:2455037:2477224247722424785521329Escherichia coli K12, complete genomeD-serine dehydratase0891
NC_010468:1412791:1430553143055314318811329Escherichia coli ATCC 8739, complete genomeD-serine ammonia-lyase0891
CP002516:1419413:1440868144086814421961329Escherichia coli KO11, complete genomeD-serine ammonia-lyase0891
AC_000091:2462461:2484648248464824859761329Escherichia coli W3110 DNA, complete genomeD-serine ammonia-lyase0891
NC_011415:2732000:2747310274731027486381329Escherichia coli SE11 chromosome, complete genomeD-serine dehydratase0891
NC_012759:2342986:2363029236302923643571329Escherichia coli BW2952 chromosome, complete genomeD-serine dehydratase0891
NC_016902:1419413:1440868144086814421961329Escherichia coli KO11FL chromosome, complete genomeD-serine ammonia-lyase0891
NC_008258:2473000:2476004247600424773321329Shigella flexneri 5 str. 8401, complete genomeD-serine dehydratase0890
CU928160:2513000:2516072251607225174001329Escherichia coli IAI1 chromosome, complete genomeD-serine ammonia-lyase0889
NC_009801:2639787:2642711264271126440391329Escherichia coli E24377A, complete genomeD-serine ammonia-lyase0889
AP010958:2911741:2930199293019929315271329Escherichia coli O103:H2 str. 12009 DNA, complete genomeD-serine ammonia-lyase DsdA0889
NC_009800:2505872:2510607251060725119351329Escherichia coli HS, complete genomeD-serine ammonia-lyase0889
NC_011741:2513000:2516072251607225174001329Escherichia coli IAI1 chromosome, complete genomeD-serine dehydratase0889
NC_012947:1363724:1381486138148613828141329Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeD-serine dehydratase0889
NC_012967:2409500:2413429241342924147571329Escherichia coli B str. REL606 chromosome, complete genomeD-serine dehydratase0889
NC_013353:2911741:2930199293019929315271329Escherichia coli O103:H2 str. 12009, complete genomeD-serine ammonia-lyase DsdA0889
CU928145:2708500:2711583271158327129111329Escherichia coli 55989 chromosome, complete genomeD-serine ammonia-lyase0888
NC_011748:2708500:2711583271158327129111329Escherichia coli 55989, complete genomeD-serine dehydratase0888
NC_004337:2478461:2482265248226524835931329Shigella flexneri 2a str. 301, complete genomeD-serine dehydratase0886
NC_004741:2456297:2460404246040424617321329Shigella flexneri 2a str. 2457T, complete genomeD-serine dehydratase0886
NC_017328:2516000:2519907251990725212351329Shigella flexneri 2002017 chromosome, complete genomeD-serine dehydratase0886
NC_013361:3313284:3337364333736433386921329Escherichia coli O26:H11 str. 11368 chromosome, complete genomeD-serine dehydratase0886
NC_002655:3260500:3277298327729832786261329Escherichia coli O157:H7 EDL933, complete genomeD-serine dehydratase0883
NC_002695:3189425:3207339320733932086671329Escherichia coli O157:H7 str. Sakai, complete genomeD-serine dehydratase0883
NC_011353:3276734:3311455331145533127831329Escherichia coli O157:H7 str. EC4115 chromosome, complete genomeD-serine dehydratase0883
NC_013008:3231414:3266326326632632676541329Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeD-serine dehydratase0883
NC_011745:2751437:2753945275394527552731329Escherichia coli ED1a chromosome, complete genomeD-serine dehydratase0882
NC_011751:2768864:2771788277178827731191332Escherichia coli UMN026 chromosome, complete genomeD-serine dehydratase0882
NC_008253:2499735:2502637250263725039651329Escherichia coli 536, complete genomeD-serine dehydratase0880
NC_007606:2353098:2356013235601323573411329Shigella dysenteriae Sd197, complete genomeD-serine dehydratase0880
NC_004431:2747237:2761590276159027629181329Escherichia coli CFT073, complete genomeD-serine dehydratase0880
NC_011750:2585015:2601004260100426023351332Escherichia coli IAI39 chromosome, complete genomeD-serine dehydratase0880
NC_011742:2533500:2536102253610225374301329Escherichia coli S88 chromosome, complete genomeD-serine dehydratase0877
NC_007946:2625461:2640470264047026417981329Escherichia coli UTI89, complete genomeD-serine dehydratase0877
NC_008563:2610499:2613007261300726143351329Escherichia coli APEC O1, complete genomeD-serine dehydratase0877
CP002797:2472908:2481834248183424831471314Escherichia coli NA114, complete genomeD-serine dehydratase0875
NC_011750:4390000:4392540439254043938711332Escherichia coli IAI39 chromosome, complete genomeD-serine dehydratase0875
NC_010498:2555706:2570037257003725713531317Escherichia coli SMS-3-5, complete genomeD-serine ammonia-lyase0867
NC_010658:2529033:2533959253395925352271269Shigella boydii CDC 3083-94, complete genomeD-serine ammonia-lyase0822
NC_007613:2376974:2381236238123623824621227Shigella boydii Sb227, complete genomeD-serine dehydratase0816
NC_016857:4025767:4025767402576740270891323Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74D-serine dehydratase0791
NC_004631:3809678:3828443382844338297651323Salmonella enterica subsp. enterica serovar Typhi Ty2, completeD-serine dehydratase0790
NC_003198:3824187:3842953384295338442751323Salmonella enterica subsp. enterica serovar Typhi str. CT18,D-serine dehydratase0790
NC_006905:3942753:3944108394410839454301323Salmonella enterica subsp. enterica serovar Choleraesuis strD-serine dehydratase0790
NC_016831:3779611:3799287379928738006091323Salmonella enterica subsp. enterica serovar Gallinarum/pullorumD-serine dehydratase0788
NC_011274:3799696:3818456381845638197781323Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91D-serine dehydratase0788
NC_016832:3798475:3817240381724038185621323Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,D-serine ammonia-lyase0788
NC_013941:2928000:2948507294850729495351029Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeD-serine ammonia-lyase0677
NC_012667:504534:5165735165735178981326Vibrio cholerae MJ-1236 chromosome 2, complete genomeD-serine dehydratase0649
NC_012583:861225:8667588667588680831326Vibrio cholerae O395 chromosome chromosome II, complete sequenceD-serine dehydratase0649
NC_012580:796387:8019208019208032451326Vibrio cholerae M66-2 chromosome II, complete sequenceD-serine dehydratase0649
NC_009456:383819:3958593958593971841326Vibrio cholerae O395 chromosome 1, complete sequenceD-serine dehydratase0649
NC_002506:822401:8279348279348292591326Vibrio cholerae O1 biovar eltor str. N16961 chromosome II, completeD-serine dehydratase0649
NC_016945:822229:8277598277598290811323Vibrio cholerae IEC224 chromosome II, complete sequenceD-serine dehydratase0648
NC_016446:522936:5284665284665297881323Vibrio cholerae O1 str. 2010EL-1786 chromosome 2, completeD-serine dehydratase0648
NC_009901:4216206:4216206421620642175311326Shewanella pealeana ATCC 700345, complete genomeD-serine ammonia-lyase0642
NC_011770:1811874:1833311183331118346571347Pseudomonas aeruginosa LESB58, complete genomeD-serine dehydratase7e-155547
NC_013223:1349000:1350483135048313518681386Desulfohalobium retbaense DSM 5692, complete genomeD-serine ammonia-lyase8e-147520
NC_010545:2025000:2036788203678820380771290Corynebacterium urealyticum DSM 7109, complete genomeD-serine dehydratase5e-136484
NC_010610:861194:8770728770728784001329Lactobacillus fermentum IFO 3956, complete genomeD-serine dehydratase2e-107389
NC_007347:3188614:3190183319018331915141332Ralstonia eutropha JMP134 chromosome 1, complete sequenceD-serine dehydratase3e-100365
NC_015726:3280000:3292343329234332936831341Cupriavidus necator N-1 chromosome 1, complete sequenceD-serine dehydratase DsdA9e-100363
NC_008528:610070:6213536213536227741422Oenococcus oeni PSU-1, complete genomeThreonine dehydratase2e-91336
UCMB5137:1:113431134312143801Bacillus atrophaeus UCMB-5137D-serine ammonia-lyase2e-88326
UCMB5137:1:108111081111332522Bacillus atrophaeus UCMB-5137D-serine dehydratase2e-45183