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Query: NC_007384:1086025:1111719 Shigella sonnei Ss046, complete genome

Start: 1111719, End: 1112357, Length: 639

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011740:1189455:119515711951571195795639Escherichia fergusonii ATCC 35469, complete genomeDNA-binding transcriptional regulator of the alternative pyrimidine degradation pathway1e-106385
NC_011147:1763681:178636117863611786999639Salmonella enterica subsp. enterica serovar Paratyphi A strtranscriptional regulator4e-94343
NC_006511:1770000:179117817911781791816639Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCputative transcriptional regulator4e-94343
NC_012125:2646792:266813126681312668769639Salmonella enterica subsp. enterica serovar Paratyphi C straintranscriptional regulator9e-94342
NC_010102:1979742:200090520009052001543639Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein9e-94342
NC_009436:1679265:169231516923151692953639Enterobacter sp. 638, complete genomeTetR family transcriptional regulator6e-92336
NC_020063:2785652:279097727909772791615639Enterobacteriaceae bacterium strain FGI 57, complete genometranscriptional regulator3e-91334
NC_016816:2953530:298857429885742989209636Pantoea ananatis LMG 5342, complete genomeHTH-type transcriptional regulator RutR6e-76283
NC_015224:2061951:206528820652882065869582Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,TetR family transcriptional regulator1e-64246
NC_008800:2127918:213056121305612131229669Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,TetR family transcriptional regulator1e-64245
NC_015556:819503:819503819503820162660Pseudomonas fulva 12-X chromosome, complete genometranscriptional regulator, TetR family1e-38159
NC_015376:2241000:224550722455072246205699Burkholderia gladioli BSR3 chromosome chromosome 2, completeTetR family transcriptional regulator2e-30132
NC_015563:4383000:440362344036234404303681Delftia sp. Cs1-4 chromosome, complete genomeTetracycline transcriptional regulator YcdC domain-containing protein2e-29128
NC_017150:2244950:227421622742162274869654Acetobacter pasteurianus IFO 3283-01-42C, complete genometranscriptional regulator TetR7e-26117
NC_013209:2337204:236647023664702367123654Acetobacter pasteurianus IFO 3283-01, complete genometranscriptional regulator TetR7e-26117
NC_017100:2339826:236909223690922369745654Acetobacter pasteurianus IFO 3283-03, complete genometranscriptional regulator TetR7e-26117
NC_017108:2337163:236642923664292367082654Acetobacter pasteurianus IFO 3283-12, complete genometranscriptional regulator TetR7e-26117
NC_017111:2337181:236644723664472367100654Acetobacter pasteurianus IFO 3283-32, complete genometranscriptional regulator TetR7e-26117
NC_017121:2337168:236643423664342367087654Acetobacter pasteurianus IFO 3283-07, complete genometranscriptional regulator TetR7e-26117
NC_017125:2339806:236907223690722369725654Acetobacter pasteurianus IFO 3283-22, complete genometranscriptional regulator TetR7e-26117
NC_017146:2339848:236911423691142369767654Acetobacter pasteurianus IFO 3283-26, complete genometranscriptional regulator TetR7e-26117
NC_008228:4696338:470983347098334710468636Pseudoalteromonas atlantica T6c, complete genometranscriptional regulator, TetR family1e-1273.2
NC_014837:2758239:275953327595332760171639Pantoea sp. At-9b chromosome, complete genomeTetR family transcriptional regulator2e-0859.3
NC_002939:173833:191349191349191960612Geobacter sulfurreducens PCA, complete genometranscriptional regulator, TetR family8e-0753.9
NC_011000:1262324:129188312918831292545663Burkholderia cenocepacia J2315 chromosome 1, complete sequenceTetR family regulatory protein8e-0753.9