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Query: NC_007384:1086025:1106889 Shigella sonnei Ss046, complete genome

Start: 1106889, End: 1107689, Length: 801

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015224:2061951:206255320625532063389837Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative hydrolase4e-50198
NC_015276:1531159:153347015334701534246777Marinomonas mediterranea MMB-1 chromosome, complete genomepyrimidine utilization protein D1e-38159
NC_008314:1202963:121068612106861211480795Ralstonia eutropha H16 chromosome 2, complete sequencepredicted hydrolase or acyltransferase (alpha/beta hydrolase superfamily)7e-1167.8
NC_013132:6385223:639643263964326397340909Chitinophaga pinensis DSM 2588, complete genomealpha/beta hydrolase fold protein3e-0756.2
NC_002932:1798869:180490818049081805678771Chlorobium tepidum TLS, complete genome3-oxoadipate enol-lactonase, putative9e-0754.3
NC_011027:303000:315245315245316015771Chlorobaculum parvum NCIB 8327, complete genomealpha/beta hydrolase fold1e-0653.9
NC_015703:754172:772842772842773651810Runella slithyformis DSM 19594 chromosome, complete genomealpha/beta hydrolase fold protein1e-0653.9
NC_007511:3512100:352931835293183530103786Burkholderia sp. 383 chromosome 2, complete sequenceAlpha/beta hydrolase1e-0653.9
NC_008543:2871747:287312228731222873907786Burkholderia cenocepacia HI2424 chromosome 2, complete sequence3-oxoadipate enol-lactonase1e-0653.5
NC_008061:2368517:239307823930782393863786Burkholderia cenocepacia AU 1054 chromosome 2, complete sequence3-oxoadipate enol-lactonase1e-0653.5
NC_011001:63986:661066610666891786Burkholderia cenocepacia J2315 chromosome 2, complete sequenceputative 3-oxoadipate enol-lactonase I1e-0653.5
NC_015856:2488297:248929024892902490120831Collimonas fungivorans Ter331 chromosome, complete genomebeta-ketoadipate enol-lactone hydrolase2e-0653.1
NC_010552:58294:604126041261197786Burkholderia ambifaria MC40-6 chromosome 2, complete sequence3-oxoadipate enol-lactonase2e-0653.1
NC_021177:6954675:6954675695467569566211947Streptomyces fulvissimus DSM 40593, complete genome3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase2e-0653.1
NC_020064:1409596:1446789144678914480451257Serratia marcescens FGI94, complete genomeputative hydrolase or acyltransferase of alpha/beta superfamily3e-0652.8
NC_020210:2044944:204937220493722050238867Geobacillus sp. GHH01, complete genomealpha/beta hydrolase fold protein3e-0652.4
NC_015563:5289875:530664153066415307405765Delftia sp. Cs1-4 chromosome, complete genome3-oxoadipate enol-lactonase4e-0652
NC_007484:2392739:241300224130022413769768Nitrosococcus oceani ATCC 19707, complete genomebiotin biosynthesis protein, BioH6e-0651.6
NC_012997:334500:334513334513335289777Teredinibacter turnerae T7901, complete genomehydrolase, alpha/beta fold family protein9e-0650.8
NC_016111:5181475:5198489519848951999011413Streptomyces cattleya NRRL 8057, complete genome3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase1e-0550.8