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Query: NC_007384:1086025:1094701 Shigella sonnei Ss046, complete genome

Start: 1094701, End: 1096881, Length: 2181

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009801:1392696:1407125140712514092572133Escherichia coli E24377A, complete genomehypothetical protein2e-177622
NC_007384:2007467:2015762201576220170391278Shigella sonnei Ss046, complete genomehypothetical protein2e-128459
NC_008258:1934479:1942294194229419439881695Shigella flexneri 5 str. 8401, complete genomehypothetical protein4e-105382
NC_013730:3956457:3970749397074939732652517Spirosoma linguale DSM 74, complete genomephage tape measure protein4e-22107
NC_013730:6471484:6490013649001364925262514Spirosoma linguale DSM 74, complete genomephage tape measure protein6e-22106
NC_002937:1548081:1567152156715215699502799Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completetail tape measure protein, putative9e-1995.9
NC_011769:2016000:2022877202287720256932817Desulfovibrio vulgaris str. 'Miyazaki F', complete genomephage tape measure protein2e-1895.1
NC_014217:4597426:4600648460064846025131866Starkeya novella DSM 506 chromosome, complete genomephage tape measure protein5e-1893.6
NC_014217:16398:1639816398184042007Starkeya novella DSM 506 chromosome, complete genomephage tape measure protein2e-1791.3
NC_020054:4848000:4916982491698249197502769Fibrella aestuarina BUZ 2 drat genomephage tape measure protein7e-1686.3
NC_020054:4933725:4939523493952349424262904Fibrella aestuarina BUZ 2 drat genomehypothetical protein1e-1482.4
NC_020211:2882093:2893957289395728961402184Serratia marcescens WW4, complete genomehypothetical protein6e-0963.2