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Query: NC_007384:1086025:1086025 Shigella sonnei Ss046, complete genome

Start: 1086025, End: 1087266, Length: 1242

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011601:1077548:1097271109727110985121242Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomeglucose-1-phosphatase/inositol phosphatase0859
NC_011740:1189455:1192225119222511934661242Escherichia fergusonii ATCC 35469, complete genomeglucose-1-phosphatase/inositol phosphatase0840
NC_020063:2785652:2800970280097028022111242Enterobacteriaceae bacterium strain FGI 57, complete genomeHistidine acid phosphatase0692
NC_013508:1862896:1867753186775318690691317Edwardsiella tarda EIB202, complete genomeglucose-1-phosphatase/inositol phosphatase0659
NC_016631:297222:3151513151513164761326Granulicella mallensis MP5ACTX8 chromosome, complete genome4-phytase6e-38158
NC_014760:299392:314782314782315762981Mycoplasma bovis PG45 chromosome, complete genomehistidine acid phosphatase family protein1e-1481.3
NC_008343:1548020:156793515679351568651717Granulibacter bethesdensis CGDNIH1, complete genome6-phytase4e-1479.3
NC_015725:670719:686333686333687325993Mycoplasma bovis Hubei-1 chromosome, complete genomehypothetical protein2e-1377