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Query: NC_007333:1457000:1462776 Thermobifida fusca YX, complete genome

Start: 1462776, End: 1463492, Length: 717

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014158:1566310:157148715714871572158672Tsukamurella paurometabola DSM 20162 chromosome, complete genomeMethyltransferase type 127e-30130
NC_015673:1794590:181610218161021816701600Corynebacterium resistens DSM 45100 chromosome, complete genomehypothetical protein4e-2098.2
NC_013521:2193203:219320321932032193805603Sanguibacter keddieii DSM 10542, complete genomeubiquinone/menaquinone biosynthesis methylase8e-1787.4
NC_013440:3870697:389123438912343891857624Haliangium ochraceum DSM 14365, complete genomeMCP methyltransferase, CheR-type9e-0857.4