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Query: NC_007146:1405459:1425068 Haemophilus influenzae 86-028NP, complete genome

Start: 1425068, End: 1425496, Length: 429

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012691:2050957:205422720542272054661435Tolumonas auensis DSM 9187, complete genomeputative transcriptional regulator, CopG/Arc/MetJ family4e-35146
NC_004349:3938:247782477825233456Shewanella oneidensis MR-1 plasmid pMR-1, complete sequencehypothetical protein8e-24108
NC_008027:5533311:554701555470155547422408Pseudomonas entomophila L48, complete genomehypothetical protein3e-1890.5
NC_015460:1687684:168999816899981690405408Gallibacterium anatis UMN179 chromosome, complete genomeputative nuclease of the RNAse H fold, HicB family5e-1786.3
NC_015379:1600715:160593816059381606348411Pseudomonas brassicacearum subsp. brassicacearum NFM421 chromosome,hypothetical protein8e-1785.9
NC_013971:1927510:193350819335081933918411Erwinia amylovora ATCC 49946 chromosome, complete genomephage protein2e-1374.3
NC_013961:1891000:189598118959811896391411Erwinia amylovora, complete genomeUncharacterized 14.9 kDa protein in rep-hol intergenic region2e-1374.3
NC_014722:846084:862363862363862833471Burkholderia rhizoxinica HKI 454, complete genomehypothetical protein3e-1167
NC_014837:1570500:158686415868641587268405Pantoea sp. At-9b chromosome, complete genomehypothetical protein8e-1062.4
NC_013971:335247:345707345707346120414Erwinia amylovora ATCC 49946 chromosome, complete genomephage protein4e-0960.1
NC_013961:3413011:342526234252623425675414Erwinia amylovora, complete genomeUncharacterized 14.9 kDa protein in rep-hol intergenic region4e-0960.1
NC_014910:1765065:176910417691041769496393Alicycliphilus denitrificans BC chromosome, complete genomeuncharacterized protein family upf01504e-0857
NC_007650:2429307:244460024446002445016417Burkholderia thailandensis E264 chromosome II, complete sequencehypothetical protein3e-0753.9
NC_006351:520500:536201536201536617417Burkholderia pseudomallei K96243 chromosome 2, complete sequencephage-related hypothetical protein4e-0753.5
NC_011901:2202690:220532222053222205750429Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completehypothetical protein2e-0650.8