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Query: NC_007146:1405459:1421660 Haemophilus influenzae 86-028NP, complete genome

Start: 1421660, End: 1422808, Length: 1149

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009567:904922:9108599108599120071149Haemophilus influenzae PittGG chromosome, complete genomehypothetical protein0791
NC_013416:1091432:1103510110351011046611152Aggregatibacter actinomycetemcomitans D11S-1, complete genomehypothetical protein0684
NC_011979:3495432:3508435350843535096221188Geobacter sp. FRC-32, complete genomeprotein of unknown function DUF4504e-117421
NC_013665:1766158:1782800178280017839811182Methanocella paludicola SANAE, complete genomehypothetical protein3e-52206
NC_010424:697187:7436247436247447721149Candidatus Desulforudis audaxviator MP104C, complete genomeprotein of unknown function DUF4505e-52205
NC_020126:7686076:7693096769309676943161221Myxococcus stipitatus DSM 14675, complete genomehypothetical protein1e-40167
NC_007005:5825925:5838180583818058392651086Pseudomonas syringae pv. syringae B728a, complete genomeProtein of unknown function DUF4507e-38158
NC_011832:1283521:1296971129697112980411071Candidatus Methanosphaerula palustris E1-9c, complete genomeprotein of unknown function DUF4506e-38158
NC_020054:6162836:6168069616806961692051137Fibrella aestuarina BUZ 2 drat genomeprotein of unknown function DUF4503e-37155
NC_014306:4901390:4910908491090849119871080Erwinia billingiae Eb661, complete genomePutative phage-related protein3e-37155
NC_002937:2933000:2941168294116829422411074Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completehypothetical protein1e-36154
NC_013132:8732093:8747109874710987481971089Chitinophaga pinensis DSM 2588, complete genomeprotein of unknown function DUF4501e-36154
NC_009138:3153576:3178357317835731794451089Herminiimonas arsenicoxydans, complete genomehypothetical protein5e-36152
NC_013730:6471484:6480887648088764819811095Spirosoma linguale DSM 74, complete genomeprotein of unknown function DUF4507e-36151
NC_003552:4714457:4718639471863947197271089Methanosarcina acetivorans C2A, complete genomehypothetical protein1e-34147
NC_007761:241900:2471892471892482441056Rhizobium etli CFN 42, complete genomehypothetical protein4e-29129
NC_014973:1598429:1609450160945016105291080Geobacter sp. M18 chromosome, complete genomehypothetical protein9e-29127
NC_014034:3111981:3131689313168931327561068Rhodobacter capsulatus SB1003 chromosome, complete genomehypothetical protein1e-28127
NC_015474:538544:552207552207553061855Pyrococcus sp. NA2 chromosome, complete genomehypothetical protein2e-1170.5
NC_015161:758929:7685497685497715062958Deinococcus proteolyticus MRP chromosome, complete genome5e-1168.9
NC_019792:2524130:2581494258149425826571164Natronobacterium gregoryi SP2 chromosome, complete genomehypothetical protein7e-0962
NC_020388:252500:2715172715172725841068Natronomonas moolapensis 8.8.11 complete genomehypothetical protein1e-0861.2
NC_019974:1909244:1923101192310119241981098Natronococcus occultus SP4, complete genomehypothetical protein3e-0860.1
NC_014829:178000:196602196602197045444Bacillus cellulosilyticus DSM 2522 chromosome, complete genomehypothetical protein2e-0757.4