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Query: NC_007146:1405459:1418040 Haemophilus influenzae 86-028NP, complete genome

Start: 1418040, End: 1418384, Length: 345

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009567:904922:915278915278915622345Haemophilus influenzae PittGG chromosome, complete genomehypothetical protein6e-63238
NC_014922:1360000:138181813818181382162345Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein2e-54210
NC_014922:825396:838877838877839224348Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein4e-40162
NC_016809:1778000:178313817831381783482345Haemophilus influenzae 10810, complete genomehypothetical protein9e-39158
NC_016809:389561:396792396792397109318Haemophilus influenzae 10810, complete genomehypothetical protein1e-36151